Results 71 to 80 of about 2,532 (196)

The Mechanism of Sevoflurane Preconditioning-Induced Protections against Small Intestinal Ischemia Reperfusion Injury Is Independent of Mast Cell in Rats

Mediators of Inflammation, 2013
The study aimed to investigate whether sevoflurane preconditioning can protect against small intestinal ischemia reperfusion (IIR) injury and to explore whether mast cell (MC) is involved in the protections provided by sevoflurane preconditioning ...
Xiaoliang Gan, Guangjie Su, Weicheng Zhao, Pinjie Huang, Gangjian Luo, Ziqing Hei   +5 more
doaj   +1 more source

Prophylaxis of food-induced migraine with cromolyn sodium: efficacy of short and long-term use

, 1989
Some food contain a wide variety of allergenic determinants that are able to provoke headache by release of neurovasoactive substances. Prophylact treatment with cromolyn sodium may chance the incidence of migraine attacks induced by provoking ...
PINI, Luigi Alberto, Giacovazzo M., FERRARI, Anna, Martelletti P, Magrone D, Centone V, Verri AP, Bussone G, Frediani F, Micieli G   +9 more
core  

Docking poses for the substrate DND and five compounds.

, 2021
A) Similar binding pose for DND (blue stick) vs Novobiocin sodium salt (cyan stick). B) Different binding poses for Carbenoxolone disodium salt, Cromolyn disodium salt, Sulfasalazine, ZINC13544129, Novobiocin salt vs DND. Compound colouring schemes shown
Melanie Grobbelaar (11636780), Ruben Cloete (173249), Mohd Shahbaaz (504871), Alan Christoffels (16635), Samantha L. Sampson (7280255)   +4 more
core   +1 more source

Mechanisms and Comparison of Anti-allergic Efficacy of Topical Lodoxamide and Cromolyn Sodium Treatment in Vernal Keratoconjunctivitis

, 2000
Purpose: To explore the mechanism of action of topical lodoxamide and cromolyn sodium treatment in vernal keratoconjunctivitis (VKC) and to compare the efficacy of these drugs to each other. Design: Single-investigator, masked, randomized, clinical trial.
Kapıcıoğlu, Zerrin, Akyol, Nurettin, Avunduk, Avni Murat, Avunduk, Mustafa Cihat, Tavlı, Lema   +4 more
core   +1 more source

Synovial microenvironment-influenced mast cells promote the progression of rheumatoid arthritis

Nature Communications
Mast cells are phenotypically and functionally heterogeneous, and their state is possibly controlled by local microenvironment. Therefore, specific analyses are needed to understand whether mast cells function as powerful participants or dispensable ...
Yunxuan Lei, Xin Guo, Yanping Luo, Xiaoyin Niu, Yebin Xi, Lianbo Xiao, Dongyi He, Yanqin Bian, Yong Zhang, Li Wang, Xiaochun Peng, Zhaojun Wang, Guangjie Chen   +12 more
doaj   +1 more source

Stress induces more serious barrier dysfunction in follicle-associated epithelium than villus epithelium involving mast cells and protease-activated receptor-2

Scientific Reports, 2017
Psychological stress has been associated with intestinal epithelial hyperpermeability, the basic process in various functional and organic bowel diseases.
Lei Zhang, Jun Song, Tao Bai, Wei Qian, Xiao-Hua Hou   +4 more
doaj   +1 more source

Activity of cromolyn sodium in dietary migraine: a double-blind placebo controlled multicenter trial

, 1991
We report the preliminary results of a multicenter double-blind placebo controlled trial on the efficacy of cromolyn sodium. We found a clear improvement of the migraine both with active drug and placebo. A possible explanation for such a positive effect
Giacovazzo M, Polito A, Centonze V, FERRARI, Anna, Nappi G, Martelletti P, Sternieri E., Bussone G, Frediani F, Micieli G   +9 more
core  

Inhibitory effect of a new orally active cedrol-loaded nanostructured lipid carrier on compound 48/80-induced mast cell degranulation and anaphylactic shock in mice

International Journal of Nanomedicine, 2017
Shreyasi Chakraborty, Nabanita Kar, Leena Kumari, Asit De, Tanmoy Bera Laboratory of Nanomedicine, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India Background: Type I hypersensitivity is an allergic reaction ...
Chakraborty S, Kar N, Kumari L, De A, Bera T   +4 more
doaj  

Current treatment approach to allergic disorders in pregnancy [PDF]

РМЖ. Мать и дитя, 2020
Current treatment approach to allergic disorders in pregnancy E.I. Borovkova1, I.M. Borovkov2, V.I. Koroleva1, A.A. Pashchenko3 1Pirogov Russian National Research Medical University, Moscow, Russian Federation 2Sechenov University, Moscow ...
Borovkova E.I., I.M. Borovkov, V.I. Koroleva, A.A. Pashchenko   +3 more
doaj  

Treatment with cromolyn sodium at early reperfusion but not before ischemia attenuates intestinal ischemia/reperfusion induced lung injury in mice

, 2012
Mast cell degranulation plays a key role in small intestinal ischemia/reperfusion (IIR)-induced lung injury. Studies showed that administration of mast cell stabilizers both before ischemia and at reperfusion can dramatically attenuate IIR injury ...
Gan, X, Hei, Z, Xia, Z, Luo, CF, Luo, GJ, Li, S   +5 more
core