Results 61 to 70 of about 4,115 (212)

Modulation of ConA-induced inflammatory ascites by histamine — Short communication [PDF]

, 2015
The early phase of the ConA-induced inflammatory ascites was studied, with special reference to histamine. Concanavalin A (ConA), a cell-surface binding lectin was injected i.p. (25 mg/kg bw) to mice.
Bach M.K., Baintner K., Baintner K., Feng D., Flessner M.F., Flessner M.F., Hook W.A., Károly Baintner, Roth J., Sullivan T.J., Takata K., Theoharides T.C., Wu N.Z.   +12 more
core   +1 more source

Congestion and Sinonasal Illness in Outer Space: A Study on the International Space Station

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 4, August 2025.
ABSTRACT Objectives This study aims to characterize quantitative data pertaining to sinonasal symptoms and their related medication use aboard the International Space Station (ISS). A secondary focus involves correlating these findings with mission parameters such as extravehicular activity (EVA) participation and mission duration.
Faizaan Khan, Koyal Ansingkar, Roshan Dongre, Zain Mehdi, Aatin K. Dhanda, Kayla Powell, Tariq Syed, Samuel E. Razmi, Isuru Somawardana, Jeffrey T. Vrabec, David Hilmers, Omar G. Ahmed, Masayoshi Takashima   +12 more
wiley   +1 more source

Meta‐Analysis: Evaluating Placebo Rates Across Outcomes in Eosinophilic Oesophagitis Randomised Controlled Trials

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 1, Page 32-43, January 2025.
This meta‐analysis evaluates the response to placebo across multiple outcome domains in eosinophilic oesophagitis trials. While > 40% of patients improve clinically on placebo (influenced by patient age and randomisation ratio), most patients do not improve histologically or endoscopically, highlighting the importance of objective disease assessment ...
Angelica Rivas, Newaz Shubidito Ahmed, Yuhong Yuan, Anila Qasim, David B. O'Gorman, Brian G. Feagan, Vipul Jairath, Albert J. Bredenoord, Evan S. Dellon, Christopher Ma   +9 more
wiley   +1 more source

Definitions, Criteria and Global Classification of Mast Cell Disorders with Special Reference to Mast Cell Activation Syndromes: A Consensus Proposal [PDF]

, 2011
Activation of tissue mast cells (MCs) and their abnormal growth and accumulation in various organs are typically found in primary MC disorders also referred to as mastocytosis.
Akin C, Akin C, Akin C, Alberto Orfao, Alvarez-Twose I, Arock M, Arredondo AR, Austen KF, Awad JA, Bodemer C, Boguslaw Nedoszytko, Bonadonna P, Butterfield JH, Castells MC, Cem Akin, Chin KW, Costa JJ, Daley T, Dean D. Metcalfe, Di Lorenzo G, Donker ML, Finkelman FD, Galli SJ, Garcia-Montero AC, Golden DB, González de Olano D, Hans-Peter Horny, Hogan AD, Horny HP, Johansson SG, Jordan JH, Joseph H. Butterfield, Karin Hartmann, Karl Sotlar, Knut Brockow, Lawrence B. Schwartz, Lieberman P, Luis Escribano, Maintz L, Mariana Castells, Massimo Triggiani, Melody C. Carter, Metcalfe DD, Metcalfe DD, Metcalfe DD, Michel Arock, Morel AM, Murphy S, Nedoszytko B, Peavy RD, Peter Valent, Philip Lieberman, Rivera J, Rudolf Valenta, Ruëff F, Samorapoompichit P, Sampson HA, Schwartz LB, Schwartz LB, Schwartz LB, Schwelberger HG, Serafin WE, Sonneck K, Sperr WR, Vadas P, Valent P, Valent P, Valent P, Valent P, Valent P, van der Donk EM, van Toorenenbergen AW, Webb LM, Wolfgang R. Sperr   +73 more
core   +1 more source

Eosinophilic Esophagitis (EoE): an emerging disease in childhood - Review of diagnostic and management strategies

Frontiers in Pediatrics, 2014
Eosinophilic esophagitis (EoE) is a chronic immune/antigen mediated inflammatory disease of the esophagus. It comprises a separate entity of increasing incidence and prevalence in children and adults. The disease is characterized by histological evidence
Jorge Amil Dias, Alexandra ePapadopoulou
doaj   +1 more source

iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer’s Disease [PDF]

, 2017
In the process of drug development, in vitro studies do not always adequately predict human-specific drug responsiveness in clinical trials. Here, we applied the advantage of human iPSC-derived neurons, which offer human-specific drug responsiveness, to ...
Arai Tetsuaki, Asada Takashi, Funayama Misato, Imamura Keiko, Inoue Haruhisa, Iwata Nobuhisa, Izumi Yuishin, Kaji Ryuji, Kawakatsu Shinobu, Kondo Takayuki, Miyake Michiyo, Nakagawa Masato, Ohta Akira, Tsukita Kayoko, Woltjen Knut, 新井 哲明   +15 more
core   +1 more source

Patient-centred pharmaceutical design to improve acceptability of medicines : similarities and differences in paediatric and geriatric populations [PDF]

, 2014
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are ...
Batchelor, Hannah K., Ernest, Terry B., Flanagan, Talia, Liu, Fang, Orlu-Gul, Mine, Ranmal, Sejal, Thomas, Iwan W., Tuleu, Catherine   +7 more
core   +3 more sources

CRF induces intestinal epithelial barrier injury via the release of mast cell proteases and TNF-α. [PDF]

PLoS ONE, 2012
Psychological stress is a predisposing factor in the onset and exacerbation of important gastrointestinal diseases including irritable bowel syndrome (IBS) and the inflammatory bowel diseases (IBD).
Elizabeth L Overman, Jean E Rivier, Adam J Moeser   +2 more
doaj   +1 more source

A trial of patient-oriented problem-solving system for immunology teaching in China: a comparison with dialectic lectures [PDF]

, 2013
BACKGROUND: The most common teaching method used in China is lecturing, but recently, efforts have been widely undertaken to promote the transition from teacher-centered to student-centered education. The patient-oriented problem-solving (POPS) system is
Junfeng Han, Sheng Guo, Wei Liu, Yuzhang Wu, Zhiren Zhang   +4 more
core   +1 more source

Postnasal drip and chronic cough in patients with chronic rhinitis treated with temperature‐controlled radiofrequency neurolysis

International Forum of Allergy &Rhinology, Volume 14, Issue 3, Page 621-629, March 2024.
Abstract Objective To evaluate the contribution of postnasal drip (PND) and chronic cough (CC) to symptoms of patients with chronic rhinitis treated with temperature‐controlled radiofrequency (TCRF) neurolysis of the posterior nasal nerve (PNN), and correlate PND and CC scores with components of the reflective total nasal symptom score (rTNSS ...
Daniel Gorelik, Jumah G. Ahmad, Samuel E. Razmi, Masayoshi Takashima, Yin Yiu, Apurva Thekdi, Murugappan Ramanathan Jr., Aatin K. Dhanda, Michael T. Yim, Omar G. Ahmed   +9 more
wiley   +1 more source