Results 41 to 50 of about 4,115 (212)

The clinical effectiveness and cost-effectiveness of inhaler devices used in the routine management of chronic asthma in older children: a systematic review and economic evaluation [PDF]

open access: yes, 2002
Background: This review examines the clinical effectiveness and cost-effectiveness of hand-held inhalers to deliver medication for the routine management of chronic asthma in children aged between 5 and 15 years.
Beverley, C.   +4 more
core   +1 more source

Evaluation of Histopathological Changes of Long-Term Use of Sodium Cromoglycate on Healthy Rat Nasal Respiratory Mucosa with Light Microscopy

open access: yesTurkish Archives of Otorhinolaryngology, 2013
Objective:To demonstrate the histopathological effects of the long-term use of cromolyn sodium on healthy rat nasal mucosa using the light microscope.Methods:The animals were grouped according to the intranasal administered agents: first group (n=10 ...
Hande Senem Deveci   +2 more
doaj   +1 more source

Mast cell targeting hampers prostate adenocarcinoma development but promotes the occurrence of highly malignant neuroendocrine cancers [PDF]

open access: yes, 2011
Mast cells (MC) are c-Kit-expressing cells, best known for their primary involvement in allergic reactions, but recently reappraised as important players in either cancer promotion or inhibition.
Colombo, M.   +7 more
core   +1 more source

G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease [PDF]

open access: yes, 2015
G protein-coupled receptor 35 (GPR35) is an orphan receptor, discovered in 1998, that has garnered interest as a potential therapeutic target through its association with a range of diseases.
Amanda E Mackenzie   +4 more
core   +3 more sources

The Effect of Cromolyn Sodium and Nedocromil Sodium Administered by A pressurized Aerosol with A spacer Device on Exercise-Induced Asthma in Children

open access: yesMediators of Inflammation, 1994
To compare the effectiveness of cromolyn sodium (CS) (10 mg) and nedocromil sodium (NS) (4 mg) administered by a metered dose inhaler (MDI) with a spacer device in preventing exercise-induced asthma (EIA), eight asthmatic children with EIA were studied ...
F. M. de Benedictis   +5 more
doaj   +1 more source

Effect of Intervention in Mast Cell Function Before Reperfusion on Renal Ischemia-Reperfusion Injury in Rats

open access: yesKidney & Blood Pressure Research, 2016
Background/Aims: Mast cells are sparsely distributed in the kidneys under normal conditions; however, the number of mast cells increases dramatically during renal ischemia/reperfusion injury (RI/RI). When mast cells are stimulated, numerous mediators are
Fei Tong, Lei Luo, Daojun Liu
doaj   +1 more source

The measurement of health-related quality of life (QOL) in paediatric clinical trials: a systematic review [PDF]

open access: yes, 2004
Background The goal of much care in chronic childhood illness is to improve quality of life (QOL). However, surveys suggest QOL measures are not routinely included.
Clarke, S., Eiser, C.
core   +3 more sources

Resveratrol Suppresses Gut-Derived NLRP3 Inflammasome Partly through Stabilizing Mast Cells in a Rat Model

open access: yesMediators of Inflammation, 2018
Background. Inflammatory responses induced by intestinal ischemia-reperfusion (IIR) lead to serious systemic organ dysfunction and pose a challenge for current treatment.
Weicheng Zhao   +7 more
doaj   +1 more source

Efficacy of Topical Applications on Reducing Uremic Pruritus: A Systematic Review

open access: yesJurnal Ners, 2020
Introduction: Uremic pruritus is an unpleasant sensation that has been recognized as a frequent complication in patients with chronic kidney disease.
Gabriel Wanda Sinawang   +3 more
doaj   +1 more source

Steroids in pediatric eosinophilic esophagitis [PDF]

open access: yes, 2014
Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids.
Contreras, Emily M., Gupta, Sandeep K.
core   +1 more source

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