Hypokalemic Periodic Paralysis in a Young Woman With Mast Cell Activation Syndrome: A Case Report of an Atypical Presentation Associated With an Ultra-Rare CACNA1S Variant. [PDF]
Clin Case RepABSTRACT Hypokalemic periodic paralysis (hKPP) is a rare neuromuscular channelopathy characterized by transient episodes of muscle weakness or paralysis associated with low serum potassium levels. It has been most commonly linked to autosomal dominant mutations in ion channel genes, specifically CACNA1S and SCN4A, which impair skeletal muscle ...
Moradi A +8 more
europepmc +2 more sources
Inhibition of Mast Cell Degranulation With Cromolyn Sodium Exhibits Organ-Specific Effects in Polycystic Kidney (PCK) Rats. [PDF]
Int J Toxicol, 2018 Autosomal recessive polycystic kidney disease (ARPKD) is a monogenic disease characterized by development of hepatorenal cysts, pericystic fibrosis, and inflammation.
Jiang L +4 more
europepmc +2 more sources
Comparison of Cromolyn Sodium, Montelukast, and Zafirlukast Prophylaxis for Capsular Contracture
, 2022 Background: Capsular contracture is the most common complication following breast augmentation. Recently, prophylaxis studies aiming to inhibit the release of profibrotic substances to prevent capsular contracture have gained in importance.
Fethiye Damla Menkü Özdemir +11 more
core +1 more source
Effects of cromolyn sodium and honey on vincristine-induced neuropathic pain: An experimental study in mice [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریزBackground. Chemotherapy-induced neuropathy is a significant side effect of anticancer drugs such as vincristine, leading to increased pain sensitivity and reduced quality of life. Investigations are required to reduce these adverse effects.
Moslem Najafi +3 more
doaj +1 more source
The role of mast cells, C-fibers, and cholinergic transmission in the reduction of tracheal muscle and mronchi of sensitized animal [PDF]
Caspian Journal of Environmental Sciences, 2020 The article considers the role of stabilization of mast cell membranes, blockade of neuromuscular transmission and inactivation of C-fibers in the contractile activity of smooth muscles of the trachea and bronchi of sensitized rats.
V.M. Kirilina +2 more
doaj +1 more source
UroPrecision, Volume 1, Issue 4, Page 162-178, December 2023., 2023 Abstract Background As one of the most common diseases in urology, a large number of preclinical studies have been accumulated to explore the etiological mechanism and potential intervention of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).
Yongfeng Lao +6 more
wiley +1 more source
CXCL10 Promotes Spinal Macrophage Recruitment via the JAK/STAT3 Pathway to Induce Pain in Experimental Autoimmune Prostatitis. [PDF]
Cell ProlifThe CXCL10/CXCR3 axis was involved in spinal macrophage infiltration through activating the JAK/STAT3 pathway. The prostate NGF/TrKA axis was involved in the neuroinflammation and pain in chronic prostatitis, and inhibition of NGF could attenuate pain response in chronic prostatitis, which provided novel therapeutic targets for pain treatment in ...
Chen L +7 more
europepmc +2 more sources
Risks and benefits of asthma therapies
Allergology International, 2000 Maintenance use of short-acting adrenergic agents can cause tachyphylaxis, increased non-specific bronchial hyperreactivity, poorer clinical control, a worsened late allergic reaction and possibly an increased risk of death; therefore, 'as needed' use is
Peter König
doaj +1 more source
Mast Cell Deficiency Protects Mice from Surgery-Induced Neuroinflammation
Mediators of Inflammation, 2020 Neuroinflammation plays a key role in the occurrence and development of neurodegenerative diseases. Microglia, the resident immune cells in the brain, have been recognized to contribute to neuroinflammation.
Xiang Zhang +3 more
doaj +1 more source