Results 151 to 160 of about 137,586 (311)

Crop genetic resource policy: the role of ex situ genebanks

open access: yes
The world-wide capacity of genebanks for ex situ conservation of crop genetic resources has increased greatly since the 1970s, improving the access of crop breeders to landraces and wild and weedy relatives.
Wright, Brian D.
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Crop diversity management: Sereer smallholders' response to climatic variability in Senegal. [PDF]

open access: yesJ Ethnobiol, 2021
Ruggieri F   +5 more
europepmc   +1 more source

Measuring the state of conservation of crop diversity : A baseline for marking progress toward biodiversity conservation and sustainable development goals [PDF]

open access: yes, 2016
Many world leaders gathered in New York last September to renew their commitment to the sustainable development of the planet by adopting the new Sustainable Development Goals (SDGs), which specifically mention the importance of plant genetic resources ...
Castaneda-Alvarez, N.P.   +9 more
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Determinants of Rice Variety Diversity on Household Farms in the Terai Region of Nepal

open access: yes
Crop genetic resources are the building block of sustainable agricultural development as these can be used to develop crop varieties adaptable to heterogeneous environmental conditions.
Bauer, Siegfried, Joshi, Ganesh R.
core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

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