FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Climate change in the Catalan Pyrenees intersects with socioeconomic factors to shape crop diversity and management. [PDF]
Agron Sustain Dev, 2022 Blanch-Ramirez J +3 more
europepmc +1 more source
Quinoa crop biodiversity in Chile: an ancient plant cultivated with sustainable agricultural practices and producing grains of outstanding and diverse nutritional values [PDF]
, 2011 Quinoa crop (Chenopodium quinoa) has been cultivated since the last seven thousand years in Latin America. However the nutritional and functional properties have been diffused only since the last decade.
Bazile, Didier +7 more
core
Effect of Four Cropping Systems on the Abundance and Diversity of Epedaphic Springtails (Hexapoda: Parainsecta: Collembola) in Southern Wisconsin [PDF]
, 2002 Eric J. Rebek +2 more
openalex +1 more source
Diversity of entomopathogenic fungi from soils of eucalyptus and soybean crops and natural forest areas [PDF]
, 2022 Maurício Magalhães Domingues +7 more
openalex +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
National-scale changes in crop diversity through the Anthropocene. [PDF]
Sci Rep, 2021 Mariani RO +5 more
europepmc +1 more source
Allelic diversity at orthologous candidate genes for drought tolerance in cereal crops: Example of the ASR gene family [PDF]
, 2008 Drought is a major abiotic stress. Many candidate genes have been proposed during the last years to explain aspects of tolerance to drought stress, for a specific crop and in a specific environment.
Baum, Michaël +8 more
core
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Global relationships between crop diversity and nutritional stability. [PDF]
Nat Commun, 2021 Nicholson CC, Emery BF, Niles MT.
europepmc +1 more source