Results 101 to 110 of about 328,667 (315)
Growth of Crop and Weeds in Growth Chambers and Outdoors
The early growth of spring barley (Hordeum ulgare L.), Brassica rapa L. ssp. oleifera (DC.) Metzger, Stellaria media (L.) Vill. and Viola arvensis Murray in growth chambers and in shading cages outdoors at different irradiance levels was compared. Leaf area and shoot dry weight were lower outdoors than in growth chambers at similar irradiance and ...
Kirsten Semb Tørresen +1 more
openaire +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
In this paper, we tested the operational capacity of an interoperable model coupling system for the irrigation scheduling (IMCIS) at an experimental cotton (Gossypium hirsutum L.) field in Northern Greece.
Hatzigiannakis, Evangelos +25 more
core +1 more source
Against the backdrop of global population and food security challenges, improving crop nitrogen use efficiency (NUE) is essential for sustainable agriculture.
Kaiwen Zhang +8 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Assessing lead-time for predicting wheat growth using a crop simulation model
In order to use crop simulation models to predict crop yield, unobserved daily weather, an important input for crop models, must be forecast in some sense.
Semenov, M. A. +3 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Effects of the second crop on maize yield and yield components in organic agriculture
The second crop use in organic agriculture is a known method of maintaining the soil tilth, soil protection against environmental deterioration, soil nutrients conservation and even the weed control.
Jug, I. +6 more
core
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

