Results 71 to 80 of about 691,747 (266)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
INCOME DIVERSIFICATION AND POVERTY REDUCTION IN THE NORTHERN UPLANDS OF VIETNAM [PDF]
In the context of the economic development, income diversification is sometimes defined as the process by which households switch from growing low-value staple food crops to growing a mix of food crops and higher-value commercial crops (crop ...
Minot, Nicholas
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Summer Annual x Fertility Rate Trial [PDF]
, 2012 Warm season grasses are high yield and quality forages best grown during the hot and dry summer months. They can provide quality pasture in the summer months when common cool season grasses are not as productive. Warm season grasses can also be harvested
Burke, Conner +5 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Uncovering Productivity Growth in the Disaggregate: Indonesia's Dueling Agricultural Sub-Sectors [PDF]
The success of seed-fertilizer technologies and government subsidies in attaining nearly self-sufficient rice production in the mid-1980s encouraged the Indonesian government soon afterward to shift resources away from food crops and toward export ...
Buccola, Steven T. +2 more
core +1 more source
NO-TILL PROVIDES THE OPPORTUNITY TO MANAGE UNDERGROUND INTERACTIONS BETWEEN ARBUSCULAR MYCORRHIZAL FUNGI, WEEDS AND CROP PLANTS UNDER MEDITERRANEAN CONDITIONS [PDF]
, 2012 Early colonization of crop roots by arbuscular mycorrhiza (AM) is considered beneficial but its importance likely depends on the possible stresses faced by the host plant. Manganese toxicity is one such stress that AM can alleviate.
Alho, Luís +3 more
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Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Rural Employment At A Glance [PDF]
Rural Employment At A Glance is a six-page brochure that highlights the most recent indicators of employment and unemployment in rural areas. It documents changes and differences in metro and nonmetro employment growth, unemployment, earnings per job ...
Kusmin, Lorin D., Parker, Timothy S.
core +1 more source