Results 131 to 140 of about 591,535 (308)

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Linkages between poverty and land management in rural Uganda: evidence from the Uganda National Household Survey, 1999/00 [PDF]

open access: yes
"This study investigates the impacts of rural poverty on farmers' land management decisions, crop production and incomes, based upon analysis of data from the 1999/2000 Uganda National Household Survey.
Edward, Kato   +3 more
core  

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

Energy input and output of a rural village in China - the cas of the "Beijing Man village" /District of Beijing [PDF]

open access: yes, 2006
The rapid development of the economy has created an increasing demand for energy in China. The limited resources of fossil energy are a risk for the development of China.
Cong, Lin   +5 more
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Local seed systems and village-level determinants of millet crop diversity in marginal environments of India: [PDF]

open access: yes
"In the subsistence-oriented, semi-arid production systems of Andhra Pradesh and Karnataka, India, the environment is marginal for crop growth and often there is no substitute for millet crops.
Nagarajan, Latha, Smale, Melinda
core  

Quinoa crop biodiversity in Chile: an ancient plant cultivated with sustainable agricultural practices and producing grains of outstanding and diverse nutritional values [PDF]

open access: yes, 2011
Quinoa crop (Chenopodium quinoa) has been cultivated since the last seven thousand years in Latin America. However the nutritional and functional properties have been diffused only since the last decade.
Bazile, Didier   +7 more
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

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