Results 121 to 130 of about 260,191 (318)

TetraRNA, a tetra-class machine learning model for deciphering the coding potential derivation of RNA world

Computational and Structural Biotechnology Journal
CncRNAs (coding and noncoding RNAs) are a class of bifunctional RNAs that that has both coding and noncoding biological activity. An increasing number of cncRNAs are being identified, prompting reassessment of our knowledge of RNA. However, most existing
Hanrui Bai, Jie Wang, Xiaoke Jiang, Zhen Guo, Wenjing Yang, Zitian Yang, Jing Li, Changning Liu   +7 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Utilization of Sunflower Crop Wild Relatives for Cultivated Sunflower Improvement

, 2017
Sunflower (Helianthus annuus L.) is one of the few crops native to the United States. The current USDA–ARS National Plant Germplasm System (NPGS) crop wild relatives sunflower collection is the largest extant collection in the world, containing 2519 ...
G. Seiler, Lili Qi, L. F. Marek
semanticscholar   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Combatting environmental impacts and microbiological pollution risks in Potato cropping: Benefits of forage cultivation in a semi-arid region

Resources, Environment and Sustainability
Continuous potato cropping in semi-arid regions, which are vulnerable to erosion, reduces tuber yields and leads to a decline in soil quality. This research delves into the impact of forage cultivation on soil bacterial and archaeal communities and the ...
Xudong Sun, Yousif Abdelrahman Yousif Abdellah, Guangyan Wang, Huasen Wang, Jishao Jiang, Yu Zhang, Caspar C.C. Chater, Yongping Yang, Yuanwen Duan, Fuqiang Yu, Dong Liu   +10 more
doaj   +1 more source

CROP WILD RELATIVES OF THE AKTOBE FRORAL DISTRICT

Труды по прикладной ботанике, генетике и селекции, 2018
For the first time crop wild relatives have been found and recorded in the Aktobe floral district. They have been catalogued in a summary of crop wild relatives which includes data on 412 species.
S. A. Aipeisova
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A revised classification of Dryopteridaceae based on plastome phylogenomics and morphological evidence, with the description of a new genus, Pseudarachniodes

Plant Diversity
Dryopteridaceae are the largest fern family and include nearly 20% of extant fern diversity, with 24 currently recognized genera. Recognition and delineation of genera within this family have varied greatly.
Zheng-Yu Zuo, Germinal Rouhan, Shi-Yong Dong, Hong-Mei Liu, Xin-Yu Du, Li-Bing Zhang, Jin-Mei Lu   +6 more
doaj   +1 more source

Estimating in situ conservation costs of Zambian crop wild relatives under alternative conservation goals

Land Use Policy, 2019
Crop wild relatives (CWR) are a globally threatened group of plants, harbouring valuable genes that are sometimes used to enhance commercial crop varieties and landraces.
Warwick Wainwright, A. Drucker, N. Maxted, J. Brehm, D. Ng’uni, D. Moran   +5 more
semanticscholar   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source