Results 101 to 110 of about 14,077 (260)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Crop Wild Relatives: A Valuable Source of Tolerance to Various Abiotic Stresses. [PDF]

Plants (Basel), 2023
Kapazoglou A, Gerakari M, Lazaridi E, Kleftogianni K, Sarri E, Tani E, Bebeli PJ.   +6 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Incorporating evolutionary and threat processes into crop wild relatives conservation. [PDF]

Nat Commun, 2022
Tobón-Niedfeldt W, Mastretta-Yanes A, Urquiza-Haas T, Goettsch B, Cuervo-Robayo AP, Urquiza-Haas E, Orjuela-R MA, Acevedo Gasman F, Oliveros-Galindo O, Burgeff C, Rivera-Rodríguez DM, Rivera-Rodríguez DM, Sánchez González JJ, Alarcón-Guerrero J, Aguilar-Meléndez A, Aragón Cuevas F, Alavez V, Alejandre-Iturbide G, Avendaño-Arrazate CH, Azurdia Pérez C, Delgado-Salinas A, Galán P, González-Ledesma M, Hernández-Ruíz J, Lorea-Hernández FG, Lira Saade R, Rodríguez A, Rodríguez Delcid D, Ruiz-Corral JA, Santos Pérez JJ, Vargas-Ponce O, Vega M, Wegier A, Quintana-Camargo M, Sarukhán J, Koleff P.   +35 more
europepmc   +1 more source

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

Advanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

Editorial: Harnessing genebanks: High-throughput phenotyping and genotyping of crop wild relatives and landraces. [PDF]

Front Plant Sci, 2023
Cortés AJ, Barnaby JY.
europepmc   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source

Cascaded regulatory network composed of small RNAs involves in the symbiosis of Panax notoginseng and fungus Acremonium sp. D212

Scientific Reports
Panax notoginseng (P. notoginseng) is a valuable traditional Chinese medical herb with multiple pharmacological effects, and Acremonium sp. D212 is a symbiotic fungus.
Baolin Yao, Haiyan Zhu, Xie He, Wenjing Yang, Chongyu Luo, Yan Li, Ao Yang, Yinhui Zhang, Lihui Jiang, Yaqiong Li, Liwei Guo, Xiahong He, Yunlong Du, Changning Liu   +13 more
doaj   +1 more source

Ecological assessment of Iris hookeriana across subalpine and alpine regions of the Hindu-Himalayas

Frontiers in Forests and Global Change
IntroductionThe Hindu-Himalayan region, a global biodiversity, hotspot harbors numerus endemic plant species that contribute significantly to ecosystem stability.
Muhammad Shakeel Khan, Shujaul Mulk Khan, Abdullah, Abdullah, Jie Liu, Jie Liu, Zeng-Yuan Wu, Zeng-Yuan Wu, Jawad Hussain, Shakil Ahmad Zeb, Nazir Mohammad, Zareena Batool, Zafeer Saqib, Rabia Afza, Fazal Manan, Shahab Ali   +15 more
doaj   +1 more source

Community-Level Incentive Mechanisms for the Conservation of Crop Wild Relatives: A Malawi Case Study. [PDF]

Plants (Basel), 2023
Drucker AG, Mponya NK, Grazioli F, Maxted N, Brehm JM, Dulloo E.   +5 more
europepmc   +1 more source