Results 101 to 110 of about 17,266 (301)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

A revised classification of Dryopteridaceae based on plastome phylogenomics and morphological evidence, with the description of a new genus, Pseudarachniodes

Plant Diversity
Dryopteridaceae are the largest fern family and include nearly 20% of extant fern diversity, with 24 currently recognized genera. Recognition and delineation of genera within this family have varied greatly.
Zheng-Yu Zuo, Germinal Rouhan, Shi-Yong Dong, Hong-Mei Liu, Xin-Yu Du, Li-Bing Zhang, Jin-Mei Lu   +6 more
doaj   +1 more source

Agrobiodiversity conservation:Securing the diversity of crop wild relatives and landraces

, 2012
Based on the 2010 conference 'Towards the establishment of genetic reserves for crop wild relatives and landraces in Europe', this book is the cutting edge discussion of agrobiodiversity conservation.
Ford-Lloyd, Brian V., Maxted, Nigel, Frese, Lothar, Pinheiro de Carvalho, Miguel A.A., Dulloo, M. Ehsan, Iriondo, José M.   +5 more
core   +1 more source

In situ plant genetic resources in Europe: crop wild relatives [PDF]

, 2021
This report describes the work of Farmer’s Pride project partners to increase knowledge about the occurrence of natural populations of crop wild relatives (CWR), as well as the existence of active in situ conservation actions.
Kell, Shelagh, Gaisberger, Hannes, Iriondo, Jose Maria, Maxted, Nigel, Rubio Teso, Maria Luisa, Lara-Romero, Carlos, Álvarez Muñiz, Clara, Magos Brehm, Joana   +7 more
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Multifaceted plant diversity patterns across the Himalaya: Status and outlook

Plant Diversity
Mountains serve as exceptional natural laboratories for studying biodiversity due to their heterogeneous landforms and climatic zones. The Himalaya, a global biodiversity hotspot, hosts rich endemic flora, supports vital ecosystem functions, and offers a
Mustaqeem Ahmad, Ya-Huang Luo, Sonia Rathee, Robert A. Spicer, Jian Zhang, Moses C. Wambulwa, Guang-Fu Zhu, Marc W. Cadotte, Zeng-Yuan Wu, Shujaul Mulk Khan, Debabrata Maity, De-Zhu Li, Jie Liu   +12 more
doaj   +1 more source

A global database for the distributions of crop wild relatives

, 2014
This poster presents the largest global database devoted to store the occurrence registers of crop wild relatives worldwide. The authors describe the multiple sources that were used as sources for such information, the curating process that this data ...
Ruth Eastwood (636246), Nigel Maxted (91829), Ruth Harker (636247), Chrystian C. Sosa (636245), Colin K. Khoury (636244), Holly Vincent (636248), Nora P. Castañeda-Álvarez (542887), Vivian Bernau (636250), Harold A. Achicanoy (636249)   +8 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

The Mating System of the Wild-to-Domesticated Complex of Gossypium hirsutum L. Is Mixed

Frontiers in Plant Science, 2018
The domestication syndrome of many plants includes changes in their mating systems. The evolution of the latter is shaped by ecological and genetic factors that are particular to an area.
Rebeca Velázquez-López, Ana Wegier, Valeria Alavez, Javier Pérez-López, Valeria Vázquez-Barrios, Denise Arroyo-Lambaer, Alejandro Ponce-Mendoza, William E. Kunin   +7 more
doaj   +1 more source

Complementary Analysis and Implementation Plan for Conservation of Crop Wild Relatives in Finland. [PDF]

Plants (Basel), 2023
Fitzgerald H, Kiviharju E, Palmé A, Hyvärinen M.   +3 more
europepmc   +1 more source