Results 101 to 110 of about 1,651,802 (314)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A fábrica das plantas globais: uma geografia da globalização das plantas da Amazônia
ConfinsFar from being an under-populated, wild or pristine region, the Amazon rainforest appears on the contrary to be a maker of global plants. What are the mechanisms of the globalization of Amazonian plants?
Bastien Beaufort
doaj +1 more source
Current achievements and future directions of physical weed control in Europe [PDF]
, 2006 This paper reviews major results achieved with physical weed control methods and strategies especially adapted for horticultural and agricultural crops.
Melander, Bo
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2013 Growing a cover crop can enhance nutrient cycling and soil health while reducing soil erosion. However, getting cover crops established in corn silage systems has historically been problematic for Northeast growers due to the length of the growing season.
Burke, Conner +4 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Perennial clovers and ryegrasses as understorey crops in cereals [PDF]
, 2003 Perennial crops undersown in cereals provide ground cover from harvest of the cereal crop to sowing of the next crop. Such cover crops can e.g. reduce soil erosion, nutrient leaching and N fertiliser requirements of the succeeding crop.
Bergkvist, Göran
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Fertilization of Agronomic Crops
EDIS, 2017 Development of fertilization programs for Florida field or forage crops requires that consideration be given to nutrient requirements for each crop, soil nutrient levels, reactions of the soil with added nutrients, and the ability of the soil to retain ...
C. Mackowiak, D.L. Wright
doaj +1 more source