Results 1 to 10 of about 89,998 (156)

Advances in Cross-Coupling Reactions [PDF]

open access: yesMolecules, 2020
Cross-coupling reactions stand among the most important reactions in chemistry [...]
José Pérez Sestelo, Luis A. Sarandeses
doaj   +3 more sources

Synthesis of fluoroalkenes and fluoroenynes via cross-coupling reactions using novel multihalogenated vinyl ethers [PDF]

open access: yesBeilstein Journal of Organic Chemistry
In this study, we develop the synthesis methods of fluoroalkenes and fluoroenynes via Suzuki–Miyaura and Sonogashira cross-coupling reactions using novel multihalogenated fluorovinyl ethers, which are easily prepared from the reaction between phenols and
Yukiko Karuo   +5 more
doaj   +2 more sources

Cross-Coupling Reaction with Lithium Methyltriolborate [PDF]

open access: yesMolecules, 2012
We newly developed lithium methyltriolborate as an air-stable white solid that is convenient to handle. The good performance of this triolborate for metal-catalyzed bond-forming reactions was demonstrated in palladium-catalyzed cross-coupling reactions ...
Norio Miyaura   +3 more
doaj   +4 more sources

Cross-coupling Reactions of Monosubstituted Tetrazines [PDF]

open access: yesOrganic Letters, 2021
A fast and mild method for the Pd-catalyzed cross-coupling reaction of monosubstituted 3-bromo-1,2,4,5-tetrazine is presented. Investigation of silver-based additives revealed that Ag2CO3 is the optimal mediator, enabling the process without the need for strong bases or high temperatures.
Hoff, Lukas V   +4 more
openaire   +3 more sources

Vinyl Esters and Vinyl Sulfonates as Green Alternatives to Vinyl Bromide for the Synthesis of Monosubstituted Alkenes via Transition-Metal-Catalyzed Reactions

open access: yesChemistry, 2023
This review summarizes the applications of vinyl sulfonate and vinyl acetate as green alternatives for vinyl bromide in cross-coupling reactions. In the first part, the preparation of vinyl sulfonates and their cross-coupling reactions are briefly ...
Tomáš Tobrman
doaj   +1 more source

Palladium-Catalyzed Cross-Coupling Reaction of Bis(cyclopentadienyl)diaryltitaniums with Terminal Alkynes

open access: yesReactions, 2023
Organotitanium compounds find application in diverse reactions, including carbon–carbon bond formation and oxidation. While titanium (IV) compounds have been used in various applications, the potential of bis(cyclopentadienyl)diaryltitanium in cross ...
Yuki Murata   +3 more
doaj   +1 more source

Impact of Cross-Coupling Reactions in Drug Discovery and Development

open access: yesMolecules, 2020
Cross-coupling reactions have played a critical role enabling the rapid expansion of structure–activity relationships (SAR) during the drug discovery phase to identify a clinical candidate and facilitate subsequent drug development processes.
Melissa J. Buskes, Maria-Jesus Blanco
doaj   +1 more source

Recent Applications of Pd-Catalyzed Suzuki–Miyaura and Buchwald–Hartwig Couplings in Pharmaceutical Process Chemistry

open access: yesOrganics, 2022
Cross-coupling reactions have changed the way complex molecules are synthesized. In particular, Suzuki–Miyaura and Buchwald–Hartwig amination reactions have given opportunities to elegantly make pharmaceutical ingredients.
Balaram S. Takale   +2 more
doaj   +1 more source

Aluminum-Catalyzed Cross Selective C3–N1′ Coupling Reactions of N-Methoxyindoles with Indoles

open access: yesChemistry, 2023
C3–N1′ bond formation of bisindoles has been a great challenge due to the intrinsic reactivity of indoles as both C3 and N1-nucleophilic character.
Keisuke Tokushige   +3 more
doaj   +1 more source

Palladium-catalyzed cross coupling reactions of 4-bromo-6H-1,2-oxazines

open access: yesBeilstein Journal of Organic Chemistry, 2009
A number of 4-aryl- and 4-alkynyl-substituted 6H-1,2-oxazines 8 and 9 have been prepared in good yields via cross coupling reactions of halogenated precursors 2, which in turn are easily accessible by bromination of 6H-1,2-oxazines 1. Lewis-acid promoted
Reinhold Zimmer   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy