Results 31 to 40 of about 90,097 (255)

Recent advances in mechanochemical metal-catalyzed cross-coupling reactions

Tetrahedron Chem
Cross-coupling reactions are key chemical transformations allowing efficient construction of structurally diverse molecules. This review surveys recent progress in metal-catalyzed cross-coupling reactions conducted under mechanochemical conditions.
Suman Yadav, Radovan Šebesta
doaj   +1 more source

Palladium(0) Deposited on PAMAM Dendrimers as a Catalyst for C–C Cross Coupling Reactions

Molecules, 2011
PAMAM dendrimers of generations G2–G3 as well as a partially substituted derivative of generation G4 and a low-molecular-weight tricyclic ligand 4 were used to bind Pd(0) nanoparticles. The obtained adducts were tested as catalysts for C–C cross-coupling
Tomasz Borkowski, Paweł Subik, Anna M. Trzeciak, Stanisław Wołowiec   +3 more
doaj   +1 more source

New insight in Hiyama cross-coupling reactions: Decarboxylative, denitrogenative and desulfidative couplings [PDF]

Chemical Review and Letters, 2018
In this mini-review, recent advances and developments in the decarboxylative, denitrogenative, and desulfidative Hiyama-type cross-coupling reaction from 2011 up present are studied.
Shahriar Sarhandi, Zahra Rahmani, Robab Moghadami, Mehdi Vali, Esmail Vessally   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Application of Nanocatalysts in C-Te Cross-Coupling Reactions: An Overview [PDF]

Chemical Review and Letters, 2018
Synthesis of organo-telluride compounds through nanoparticles catalyzed C-Te cross-coupling reactions has drawn considerable attention in the past several years. This mini review is an attempt to highlight the most important advances and contributions in
Shahram Mohammadi, Mahla Musavi, Fatemeh Abdollahzadeh, Shahram Babadoust, Akram Hosseinian   +4 more
doaj   +1 more source

Magnetically Recoverable Nanoparticulate Catalysts for Cross-Coupling Reactions: The Dendritic Support Influences the Catalytic Performance

Nanomaterials, 2021
Carbon-carbon cross-coupling reactions are among the most important synthetic tools for the preparation of pharmaceuticals and bioactive compounds. However, these reactions are normally carried out using copper, phosphines, and/or amines, which are ...
Nina V. Kuchkina, Svetlana A. Sorokina, Alexey V. Bykov, Mikhail G. Sulman, Lyudmila M. Bronstein, Zinaida B. Shifrina   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source