Results 51 to 60 of about 5,641,250 (247)

Assembly of (hetero)aryl sulfilimines via copper-catalyzed enantioselective S-arylation of sulfenamides with (hetero)aryl Iodides

Nature Communications
The (hetero)aryl sulfoximines are important structures for developing bioactive molecules, whose synthesis relies on oxidation of (hetero)aryl sulfilimines. However, asymmetric approaches for assembling (hetero)aryl sulfilimines are still rare.
Mingchuang He, Rongxing Zhang, Tongkun Wang, Xiao-Song Xue, Dawei Ma   +4 more
doaj   +1 more source

Mechanistic Insights into Nickamine-catalyzed Alkyl-Alkyl Cross-coupling Reactions

CHIMIA, 2014
Within the last decades the transition metal-catalyzed cross-coupling of non-activated alkyl halides has significantly progressed. Within the context of alkyl-alkyl cross-coupling, first row transition metals spanning from iron, over cobalt ...
Jan Breitenfeld, Xile Hu
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Cu(I)-catalysed chemo-, regio-, and stereoselective radical 1,2-carboalkynylation with two different terminal alkynes

Nature Communications
Transition-metal-catalysed asymmetric multicomponent reactions with two similar substrates often suffer from the lack of strategies to control the chemo-, regio-, and stereoselectivity of these substrates due to the close similarity in the chemical ...
Jun-Qian Bian, Li Qin, Li-Wen Fan, Jiajia Fu, Yong-Feng Cheng, Yu-Feng Zhang, Qiao Song, Peng-Fei Wang, Zhong-Liang Li, Qiang-Shuai Gu, Peng Yu, Jun-Bin Tang, Xin-Yuan Liu   +12 more
doaj   +1 more source

Recent advances in mechanochemical metal-catalyzed cross-coupling reactions

Tetrahedron Chem
Cross-coupling reactions are key chemical transformations allowing efficient construction of structurally diverse molecules. This review surveys recent progress in metal-catalyzed cross-coupling reactions conducted under mechanochemical conditions.
Suman Yadav, Radovan Šebesta
doaj   +1 more source

Palladium(0) Deposited on PAMAM Dendrimers as a Catalyst for C–C Cross Coupling Reactions

Molecules, 2011
PAMAM dendrimers of generations G2–G3 as well as a partially substituted derivative of generation G4 and a low-molecular-weight tricyclic ligand 4 were used to bind Pd(0) nanoparticles. The obtained adducts were tested as catalysts for C–C cross-coupling
Tomasz Borkowski, Paweł Subik, Anna M. Trzeciak, Stanisław Wołowiec   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Mechanisms of cross-dehydrogenative-coupling reactions

, 2015
The efficiency and simplicity of cross-dehydrogenative-coupling (CDC) reactions have captured the imagination of the organic chemical community. If we are to understand and predict these processes we must understand how they work.
Tsang, Althea S.-K, Todd, Matthew H, Park, Soo J   +2 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Application of Nanocatalysts in C-Te Cross-Coupling Reactions: An Overview [PDF]

Chemical Review and Letters, 2018
Synthesis of organo-telluride compounds through nanoparticles catalyzed C-Te cross-coupling reactions has drawn considerable attention in the past several years. This mini review is an attempt to highlight the most important advances and contributions in
Shahram Mohammadi, Mahla Musavi, Fatemeh Abdollahzadeh, Shahram Babadoust, Akram Hosseinian   +4 more
doaj   +1 more source