Dimsyl Anion Enables Visible-Light-Promoted Charge Transfer in Cross-Coupling Reactions of Aryl Halides [PDF]
A simple and mild methodology is reported for visible-light-promoted synthesis of unsymmetrical chalconides ena- bled by dimsyl anion in the absence of transition-metals or photoredox catalysts. The cross-coupling reaction between aryl halides and diaryl
Amara, Spencer +3 more
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A Paradigm Shift in Catalysis: Electro- and Photomediated Nickel-Catalyzed Cross-Coupling Reactions [PDF]
Transition-metal cata-lyzed cross-coupling reactions are fundamental reactions in organic chemistry, facilitating strategic bond formations for accessing natural products, organic mate-rials, agrochemicals, and pharmaceuticals.
Megan, Emmanuel +2 more
core +1 more source
Deaminative vinylation and arylation cross-coupling reactions
Watson, Mary P.This thesis focuses on nickel-catalyzed vinylation and arylation cross-coupling reactions via C-N bond activation. Chapter 1 describes a vinylation method that was inspired by an analogous alkylation.
Lucas Baca, Diana
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Impact of Cross-Coupling Reactions in Drug Discovery and Development
Cross-coupling reactions have played a critical role enabling the rapid expansion of structure–activity relationships (SAR) during the drug discovery phase to identify a clinical candidate and facilitate subsequent drug development processes.
Melissa J. Buskes, Maria-Jesus Blanco
doaj +1 more source
Transition Metal Catalyzed Cross-Coupling Reactions
Transition metal-catalyzed cross-coupling reactions have proved to be powerful tools for carbon–carbon as well as carbon–heteroatom bond formation in the development of synthetic methodologies for applications ranging from pharmaceuticals to materials ...
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Ni-Catalyzed Electrochemical C(sp2)−C(sp3) Cross-Coupling Reactions [PDF]
Nickel (Ni) catalyzed carbon-carbon (C−C) cross-coupling has been considerably developed in last decades and has demonstrated unique reactivities compared to palladium.
maowei, hu +4 more
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Aluminum-Catalyzed Cross Selective C3–N1′ Coupling Reactions of N-Methoxyindoles with Indoles
C3–N1′ bond formation of bisindoles has been a great challenge due to the intrinsic reactivity of indoles as both C3 and N1-nucleophilic character.
Keisuke Tokushige +3 more
doaj +1 more source
Cross-coupling reactions have changed the way complex molecules are synthesized. In particular, Suzuki–Miyaura and Buchwald–Hartwig amination reactions have given opportunities to elegantly make pharmaceutical ingredients.
Balaram S. Takale +2 more
doaj +1 more source
Oxidative Photocatalytic Homo- and Cross-Coupling of Phenols: Non-Enzymatic, Catalytic Method for Coupling Tyrosine [PDF]
The first, oxidative photocatalytic method for phenol-phenol homo-coupling and cross-coupling is described and isolated yields of up to 97% are obtained.
Philip H., Gilmartin +2 more
core +1 more source
A convenient catalyst system for microwave accelerated cross-coupling of a range of aryl boronic acids with aryl chlorides [PDF]
Article number 18A convenient microwave accelerated cross-coupling procedure between aryl chlorides with a range of boronic acids has been developed. An explanation for the low reactivity of highly fluorinated boronic acids in Suzuki coupling is provided.
Matthew L. Clarke +9 more
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