Results 61 to 70 of about 665,613 (290)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Collagen cross-linking beyond corneal ectasia: A comprehensive review
Indian Journal of OphthalmologyThe history of corneal cross-linking (CXL) dates back to 2003 when some German scientists investigated possible treatments to harden the corneal structure to increase its resistance in ectatic corneal diseases.
Grigory A Osipyan +2 more
doaj +1 more source
eXPRESS Polymer Letters, 2015 A 2,4,6-trinitrobenzenesulphonic acid (TNBS)-based assay is developed to determine the degree of chemical cross-linking in aspartic acid-based polymer gels.
B. Gyarmati +3 more
doaj +1 more source
How does Cross-Linking Effect the Thermal Stability of Polyisoprene [PDF]
, 2000 Polyisoprene can be cross-linked by an initial lithiation followed by reaction with both monochloro compounds and dichloro compounds. The monochloro compounds effect crosslinking through a lithium-chlorine exchange route while the use of dichloro ...
Wilkie, Charles A., Yao, Qiang
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Indian Journal of OphthalmologyPurpose: To evaluate changes in corneal backscattering after collagen cross-linking (CXL) for progressive keratoconus and compare its course with different techniques – standard epithelium-off CXL (SCXL), contact lens-assisted CXL (CACXL), and ...
Barkha Gupta +5 more
doaj +1 more source
Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes
, 2014 The study of proteins and protein complexes using chemical cross-linking followed by the MS identification of the cross-linked peptides has found increasingly widespread use in recent years.
Aebersold, R. +6 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
BMC Ophthalmology, 2019 Background To investigate the efficacy and safety of the retention ring-assisted continuous application of 0.1% riboflavin in pulsed-light accelerated corneal collagen cross-linking on the progression of keratoconus.
Chung Young Kim, Mee Kum Kim
doaj +1 more source
Viscoelastic behaviour of polymethyl methacrylate networks with different crosslinking degrees [PDF]
, 2004 The influence of the cross-linking degree on the dynamics of the segmental motions close to the glass transition of poly(methyl methacrylate), PMMA, networks was investigated by three different mechanical spectroscopy techniques: thermally stimulated ...
Alves N. M. +17 more
core +1 more source