Results 51 to 60 of about 7,880,106 (328)

Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection

bioRxiv, 2020
Pre-existing immune responses to seasonal endemic coronaviruses could have profound consequences for antibody responses to SARS-CoV-2, either induced in natural infection or through vaccination. Such consequences are well established in the influenza and
G. Song, Wan-ting He, Sean Callaghan, F. Anzanello, Deli Huang, James Ricketts, J. Torres, N. Beutler, Linghang Peng, Sirena Vargas, Jon Cassell, M. Parren, Linlin Yang, C. Ignacio, Davey M. Smith, J. Voss, D. Nemazee, A. Ward, T. Rogers, D. Burton, R. Andrabi   +20 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

COVID-19 infection among healthcare workers: a cross-sectional study in southwest Iran

Virology Journal, 2020
With the novel coronavirus pandemic, the impact on the healthcare system and workers cannot be overlooked. However, studies on the infection status of medical personnel are still lacking. It is imperative to ensure the safety of health-care workers (HCWs)
G. Sabetian, M. Moghadami, Leila Hashemizadeh Fard Haghighi, Reza Shahriarirad, M. Fallahi, N. Asmarian, Y. Moeini   +6 more
semanticscholar   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Incidental Detection of Giardia duodenalis via Cytologic Sampling in Pancreatic Tumor Investigation

Clinical Case Reports
Giardia duodenalis can be incidentally detected during pancreatic tumor evaluation via cytology. Even in asymptomatic patients without risk factors, recognition is essential.
Yoshiro Hadano, Koji Endo
doaj   +1 more source

In vitro effectiveness of an aqueous extract of Neem (Azadirachta indica A. Juss) leaves on bacteria causing healthcare associated infection in Valledupar

Vitae, 2021
Background: Globally, the need to address strategies for preventing infections associated with health care has increased worldwide. In the city of Valledupar, Colombia, reports of bacteria resistant to chemical or enzymatic biocides in hospital ...
Aslenis Emidia Melo Rios, Hedilka Jimenez Rios, Bertilda Pedraza Claros, Jeraldin Castrillon Mejia, Ailyn Fuentes Arias   +4 more
doaj   +1 more source

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

Nature Communications, 2020
Since 2002, beta coronaviruses (CoV) have caused three zoonotic outbreaks, SARS-CoV in 2002–2003, MERS-CoV in 2012, and the newly emerged SARS-CoV-2 in late 2019. However, little is currently known about the biology of SARS-CoV-2.
Xiuyuan Ou, Yan Liu, X. Lei, Pei Li, Dan Mi, L. Ren, Li Guo, Ruixuan Guo, Ting Chen, Jiaxin Hu, Zichun Xiang, Z. Mu, Xing Chen, Jieyong Chen, Keping Hu, Q. Jin, Jianwei Wang, Zhaohui Qian   +17 more
semanticscholar   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Analysis of the Infection Status of Healthcare Workers in Wuhan During the COVID-19 Outbreak: A Cross-sectional Study

Clinical Infectious Diseases, 2020
Background Healthcare workers (HCWs) at the frontline are facing a substantial risk of infection during the coronavirus disease 2019 (COVID-19) outbreak. Methods We acquired information and data on general information on and infection and death status of
Lichun Zheng, Xiang Wang, Chongchong Zhou, Qin Liu, Shuang Li, Qin Sun, Mengjia Wang, Qian Zhou, Wenmei Wang   +8 more
semanticscholar   +1 more source