Results 91 to 100 of about 708,583 (355)

Recent Advances in Noble Metal Nanocatalysts for Suzuki and Heck Cross-Coupling Reactions

open access: yesMolecules, 2010
Since metal nanoparticles have a high surface-to-volume ratio and very active surface atoms, they are very attractive catalysts for a wide variety of organic and inorganic reactions, compared to bulk catalysts.
Radha Narayanan
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Organophosphates as Versatile Substrates in Organic Synthesis

open access: yesMolecules
This review summarizes the applications of organophosphates in organic synthesis. After a brief introduction, it discusses cross-coupling reactions, including both transition-metal-catalyzed and transition-metal-free substitution reactions. Subsequently,
Petr Oeser, Tomáš Tobrman
doaj   +1 more source

THE LATEST ADVANCEMENTS IN THE ACYLATION REACTIONS VIA CROSS-DEHYDROGENATIVE COUPLING AND/OR METAL CATALYSTS

open access: yesJournal of the Turkish Chemical Society, Section A: Chemistry, 2017
There are quite many examples in the scientific literature regarding the acylation reactions, especially the metal-catalyzed acylation reactions, metal-free acylation reactions, metal-catalyzed acylation via cross-dehydrogenative coupling (CDC) reactions
Soykan Ağar, Ömer Tahir Günkara
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Nickel-Catalyzed Enantioselective Reductive Cross-Coupling Reactions [PDF]

open access: yes, 2020
Nickel-catalyzed reductive cross-coupling reactions have emerged as powerful methods to join two electrophiles. These reactions have proven particularly useful for the coupling of sec-alkyl electrophiles to form stereogenic centers; however, the ...
Reisman, Sarah E.   +2 more
core  

Photocatalyzed Transition-Metal-Free Oxidative Cross-Coupling Reactions of Tetraorganoborates

open access: yes, 2020
Readily accessible tetraorganoborate salts undergo selective coupling reactions under blue light irradiation in the presence of catalytic amounts of transition-metal-free acridinium and rhodamine photocatalysts to furnish unsymmetrical biaryls ...
Thomas C., Jagau   +6 more
core   +1 more source

Perceived parental reactions to coming out, attachment, and romantic relationship views [PDF]

open access: yes, 2011
Coming out as lesbian, gay, or bisexual (LGB) to one’s parents can be a challenging experience and may lead to acceptance or rejection. Attachment theory can help predict parents’ reactions to coming out and consequences for romantic attachment.
EG, Hepper   +14 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Nuclear reactions cross sections (n, x) on dysprosium and ytterbium isotopes [PDF]

open access: yesЯдерна фізика та енергетика, 2011
Cross sections of nuclear reactions 162,163Dy(n, x)162Tb, 163,164Dy(n, x)163Tb, 156Dy(n, 2n)155Dy, 158Dy(n, 2n)157(m+g)Dy, 166,167Er(n, x)166gHo, 170Er(n, p)170gHo were measured and presented for incident neutron energy (14.6 ± 0.2) MeV. The measurements
N. R. Dzysiuk   +3 more
doaj  

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