Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Peroxidase-mediated cross-linking of bovine a-lactalbumin [PDF]
, 2010 The research presented in this thesis aimed at controlling the horseradish peroxidase-catalyzed cross-linking of bovine α lactalbumin and the implications of this cross-linking for the foam stabilizing properties. Attention is also given to microreactors
Heijnis, W.H.
core
Highly Stereospecific, Cross-Coupling Reactions of Alkenylsilacyclobutanes [PDF]
, 2016 Highly Stereospecific, Cross-Coupling Reactions of ...
Jun Young Choi (566818) +1 more
core +1 more source
Nuclear reactions cross sections (n, x) on dysprosium and ytterbium isotopes [PDF]
Ядерна фізика та енергетика, 2011 Cross sections of nuclear reactions 162,163Dy(n, x)162Tb, 163,164Dy(n, x)163Tb, 156Dy(n, 2n)155Dy, 158Dy(n, 2n)157(m+g)Dy, 166,167Er(n, x)166gHo, 170Er(n, p)170gHo were measured and presented for incident neutron energy (14.6 ± 0.2) MeV. The measurements
N. R. Dzysiuk +3 more
doaj
Unravelling Antigenic Cross-Reactions toward the World of Coronaviruses: Extent of the Stability of Shared Epitopes and SARS-CoV-2 Anti-Spike Cross-Neutralizing Antibodies. [PDF]
Pathogens, 2023 Devaux CA, Fantini J.
europepmc +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Enantioselective Ni-catalyzed reductive cross-coupling reactions [PDF]
, 2016 Nickel-catalyzed reductive cross-coupling reactions have emerged as direct bond formation. These reactions typically tolerate an array of functional groups, and employ inexpensive, earth abundant metals as stoichiometric reductants.
Reisman, Sarah
core
Carbon-Carbon Cross Coupling Reactions in Ionic Liquids Catalysed by Palladium Metal Nanoparticles
Molecules, 2010 A brief summary of selected pioneering and mechanistic contributions in the field of carbon-carbon cross-coupling reactions with palladium nanoparticles (Pd-NPs) in ionic liquids (ILs) is presented.
Martin H. G. Prechtl +2 more
doaj +1 more source
Evidence of IgE-Mediated Cross-Reactions between Anisakis simplex and Contracaecum osculatum Proteins. [PDF]
Pathogens, 2021 Mehrdana F +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source