Results 101 to 110 of about 585,532 (315)
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
Capture cross sections for heavy-ion reactions producing compound system with Z = 12 [PDF]
The fusion cross sections for reactions 50Ti + 249Cf, 54Cr + 248Cm, 58Fe + 244Pu and 64Ni + 238U are evaluated in the framework of simple barrier-penetration model, which takes into account quadrupole and hexadecapole surface deformations of nuclei.
N. A. Pilipenko, V. Yu. Denisov
doaj
Cross-Reactions of Glucose-Containing Polysaccharides in Antipneumococcal Sera [PDF]
Michael Heidelberger
openalex +1 more source
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo+11 more
wiley +1 more source
The Direct lodination of Polyalkylbenzenes by the Crossed Jacobsen Reaction [PDF]
Hitomi Suzuki+2 more
openalex +1 more source
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan+4 more
wiley +1 more source
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella+18 more
wiley +1 more source
The Fukuyama Cross-Coupling Reaction [PDF]
Mark Lautens, Randy Sanichar
openaire +1 more source
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
Cross section of γ-rays irradiation in reactions of neutron absorption by iron [PDF]
Differential cross sections of the reactions natFe(n, xγ) with neutron energy 14.1 MeV are unfolded from instrumental spectra using regularization procedure by Tikhonov and algorithm on the compact set of limited variations.
V. M. Bondar+4 more
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