Results 71 to 80 of about 2,623,133 (264)
Breast Cancer Diagnosis Using Machine Learning and PSO
Tehnički GlasnikHealthcare systems around the world are facing huge challenges in responding to trends of the rise of chronic diseases. Early detection of breast cancer is essential for successful treatment since it is a common and potentially fatal condition.
Sarita Silaich, Rajesh Yadav
doaj +1 more source
An Experimental Evaluation of Nearest Neighbour Time Series Classification [PDF]
, 2014 Data mining research into time series classification (TSC) has focussed on alternative distance measures for nearest neighbour classifiers. It is standard practice to use 1-NN with Euclidean or dynamic time warping (DTW) distance as a straw man for ...
Bagnall, Anthony, Lines, Jason
core +1 more source
Construction and evaluation of classifiers for forensic document analysis
, 2011 In this study we illustrate a statistical approach to questioned document examination. Specifically, we consider the construction of three classifiers that predict the writer of a sample document based on categorical data.
Davis, Linda J. +4 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
DesimalThe Brown and Holt DES method effectively captures trends in time-series data. Its forecasting accuracy heavily depends on the selection of optimal smoothing parameters. Often, the smoothing parameters are selected manually using trial and error methods.
Chelsea Fatihah Rahma +3 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Cross-Validation Without Doing Cross-Validation in Genome-Enabled Prediction
G3 Genes|Genomes|Genetics, 2016 AbstractCross-validation of methods is an essential component of genome-enabled prediction of complex traits. We develop formulae for computing the predictions that would be obtained when one or several cases are removed in the training process, to become members of testing sets, but by running the model using all observations only once.
Daniel Gianola, Chris-Carolin Schön
openaire +3 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Comparison of Lasso and stepwise regression technique for wheat yield prediction
Journal of Agrometeorology, 2019 Multiple regression approach has been used to forecast the crop production widely. This study has been undertaken to evaluate the performance of stepwise and Lasso (Least absolute shrinkage and selection operator) regression technique in variable ...
SUDHEER KUMAR, S.D. ATTRI, K.K. SINGH
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source