Results 91 to 100 of about 2,124,367 (296)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

[News Clip: White crosses]

open access: yes, 1960
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about the 20-30 Club of Fort Worth putting up white crosses where traffic fatalities occurred in the ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

A major genetic locus in Trypanosoma brucei is a determinant of host pathology [PDF]

open access: yes, 2009
The progression and variation of pathology during infections can be due to components from both host or pathogen, and/or the interaction between them. The influence of host genetic variation on disease pathology during infections with trypanosomes has ...
C. Michael R. Turner   +25 more
core   +1 more source

CIMMYT Maize Genetic Resource Lines

open access: yes, 2020
CIMMYT makes available to the public a set of maize inbred lines called CIMMYT Maize Genetic Resource Lines (CMGRL). The CMGRLs are derived from crosses between elite CIMMYT lines and landrace accessions, populations or synthetics from the CIMMYT ...
Carvalho Andrade, Marcela   +5 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Detection of quantitative trait loci for backfat thickness and intramuscular fat content in pigs (Sus scrofa) [PDF]

open access: yes, 1999
In an experimental cross between Meishan and Dutch Large White and Landrace lines, 619 F(2) animals and their parents were typed for molecular markers covering the entire porcine genome.
van der Poel, J J   +9 more
core  

Origins of the amphiploid species Brassica napus L. investigated by chloroplast and nuclear molecular markers [PDF]

open access: yes, 2010
Background: The amphiploid species Brassica napus (oilseed rape, Canola) is a globally important oil crop yielding food, biofuels and industrial compounds such as lubricants and surfactants.
Allender, Charlotte J   +9 more
core   +1 more source

Genetic variability, correlation and path coefficient studies in F2 generation of short slender aromatic and medium slender non-aromatic rice (Oryza sativa L.)

open access: yesElectronic Journal of Plant Breeding, 2020
Genetic variability, correlation, direct and indirect effects between yield and yield component traits were studied in the F2 population of MDU 6 × VGD 1 and Improved Samba Mashuri × VGD 1 for six characters.
R. Sathishkumar, R. P. Gnanamalar, R. Suresh, G. Anand and S. Vellaikumar
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Diversity of genetic crosses used.

open access: yes, 2019
(A) Origin of 451 natural accessions (red dots) and the 450 hybrids between them (blue connecting lines). (B) Relationship between pairwise genetic distances and pairwise geographic distances.
Detlef Weigel (54320)   +5 more
core   +1 more source

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