Results 101 to 110 of about 263,045 (309)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Frontiers in Genetics, 2012 Complex Mus Musculus crosses e.g. heterogeneous stock, provide increased resolution for quantitative trait loci detection. However, increased genetic complexity challenges detection methods, with discordant results due to low data quality or complex ...
Ovidiu Dan Iancu +7 more
doaj +1 more source
Analysis of reproductive performances during the formation of a synthetic rabbit strain
, 2005 [EN] In 1995, a synthetic rabbit strain ('2666') was formed at INRA for commercial meat purposesby crossing the INRA '2066' strain and the 'V' strain from the Polytechnical University of Valencia (Spain).The development of some reproductive traits and ...
Baselga, M., Brun, J.M.
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Patterns of reproductive isolation in toads.
PLoS ONE, 2008 Understanding the general features of speciation is an important goal in evolutionary biology, and despite significant progress, several unresolved questions remain.
John H Malone, Brian E Fontenot
doaj +1 more source
, 2010 Genomic imprinting has been thought to play an important role in seed development in flowering plants. Seed in a flowering plant normally contains diploid embryo and triploid endosperm.
Cui, Yuehua, Li, Gengxin
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Integration of genetic and physical maps of the Primula vulgaris S locus and localization by chromosome in situ hybridization [PDF]
, 2015 •Heteromorphic flower development in Primula is controlled by the S locus. The S locus genes, which control anther position, pistil length and pollen size in pin and thrum flowers, have not yet been characterized.
Altenburg E +20 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Breeding for sustainable palm oil [PDF]
, 2011 As an actor of a supply chain, seed producers must take into account the impact of their work on sustainability. This is particularly true when one works on oil palm, a highly sensitive crop which is questioned on its social and environmental impact ...
Amblard, Philippe +8 more
core
INTERFERENCE IN GENETIC CROSSING OVER AND CHROMOSOME MAPPING
Genetics, 1979 ABSTRACT This paper proposes a general model for interference in genetic crossing over. The model assumes serial Occurrence of chiasmata, visualized as a renewal process along the paired (or pairing) chromosomes. This process is described as an underlying Poisson process in which the Ist, n + 1th, 2n + 1th, etc., events are to be ...
openaire +3 more sources