Results 131 to 140 of about 372,355 (336)
Isolation and Characterization of Glycerol-3-Phosphate Dehydrogenase-Defective Mutants of \u3cem\u3eNeurospora crassa\u3c/em\u3e [PDF]
, 1978 Three glycerol-nonutilizing mutants deficient in the mitochondrial glycerol-3-phosphate (G3P) dehydrogenase (EC 1.1.99.5) were isolated from inlts derivatives of Neurospora crassa following inositolless death at elevated temperatures on minimal glycerol ...
Courtright, James B., Denor, Patrick F.
core +1 more source
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Effects of Epistasis and Pleiotropy on Fitness Landscapes [PDF]
arXiv, 2013 The factors that influence genetic architecture shape the structure of the fitness landscape, and therefore play a large role in the evolutionary dynamics. Here the NK model is used to investigate how epistasis and pleiotropy -- key components of genetic architecture -- affect the structure of the fitness landscape, and how they affect the ability of ...
arxiv
Heritability and Genes Governing Number of Seeds per Pod in West African Okra Abelmoschus caillei (A. Chev.) Stevels. [PDF]
, 2013 Heritability and genetic action moderating the inheritance of number of seeds per pod was investigated in four crosses of West African Okra accessions. Parents with variation for number of seeds per pod were used in hybridization process.
Adewusi, O.F., Kehinde, O.B., Ojo, D.K.
core +1 more source
Restriction Fragment Length Polymorphism Linkage Map for Arabidopsis thaliana [PDF]
, 1988 We have constructed a restriction fragment length polymorphism linkage map for the nuclear genome of the flowering plant Arabidopsis thaliana. The map, containing 90 randomly distributed molecular markers, is physically very dense; >50% of the genome is ...
Bowman, John L. +4 more
core +1 more source
Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Silva Fennica, 2012 Hybrid aspen (Populus tremula L. Populus tremuloides Michx.) plantations are expanding in Fennoscandia and the Baltic countries; however, the possible effects of plantations on the native European aspen (P.
Koivuranta, Leena +2 more
doaj +1 more source
Variable selection with genetic algorithms using repeated cross-validation of PLS regression models as fitness measure [PDF]
arXiv, 2017 Genetic algorithms are a widely used method in chemometrics for extracting variable subsets with high prediction power. Most fitness measures used by these genetic algorithms are based on the ordinary least-squares fit of the resulting model to the entire data or a subset thereof. Due to multicollinearity, partial least squares regression is often more
arxiv
Searching for interacting QTL in related populations of an outbreeding species [PDF]
, 2009 Many important crop species are outbreeding. In outbreeding species the search for genes affecting traits is complicated by the fact that in a single cross up to four alleles may be present at each locus.
Bink, M.C.A.M. +3 more
core +2 more sources
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source