Results 131 to 140 of about 10,813,555 (336)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Computing crossing numbers

, 2009
Das Kreuzungszahlproblem wird von Graphentheoretikern seit über 60 Jahren betrachtet, jedoch ist noch immer sehr wenig über dieses einfache und zugleich hochkomplizierte Ma der Nichtplanarität bekannt. Die Aufgabenstellung ist simpel: Gegeben ein Graph, zeichnen Sie ihn mit der kleinstmöglichen Anzahl an Kantenkreuzungen.
openaire   +3 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

From the Crossing Numbers of K₅ + P_n and K₅ + C_n to the Crossing Numbers of W_m + S_n and W_m + W_n

Axioms
The crossing number of a graph is a significant measure that indicates the complexity of the graph and the difficulty of visualizing it. In this paper, we examine the crossing numbers of join products involving the complete graph K5 with discrete graphs,
Michal Staš, Jana Fortes, Mária Švecová   +2 more
doaj   +1 more source

METODE EXPONENTIAL SMOOTHING EVENT BASED (ESEB) DAN METODE WINTER’S EXPONENTIAL SMOOTHING (WES) UNTUK PERAMALAN JUMLAH PENUMPANG TIBA DI PELABUHAN PENYEBERANGAN GORONTALO

Barekeng, 2019
Forecasting the number of passengers can be a consideration for managers of Gorontalo Crossing Port regarding the provision of tickets. The number of passengers can be influenced by certain seasonal or special events.
Muhammad Rezky Friesta Payu, N. Nurwan
doaj   +1 more source

On the last time and the number of boundary crossings related to the strong law of large numbers and the law of the iterated logarithm [PDF]

, 1976
Tze Leung Lai, K. K. Gordon Lan
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Study of Drivers’ Behaviour at a Passive Railway Crossing

Promet (Zagreb), 2012
Problem: The number of killed and injured persons in incidents at railway level crossings is generally increasing on the Serbian Railways, particularly at passive crossings. In this paper we researched the direct behaviour of road traffic participants at
Sandra Kasalica, Radisav Vukadinović, Vojkan Lučanin   +2 more
doaj   +1 more source

On the number of crossings in the spectrum of a hermitian matrix which depends on a real parameter [PDF]

, 1971
T.P. Valkering
openalex   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source