Results 21 to 30 of about 135,290 (266)

Computational and Experimental Characterization of Aligned Collagen across Varied Crosslinking Degrees

Micromachines
Collagen-based scaffolds have been widely used in tissue engineering. The alignment of collagen fibers and the degree of crosslinking in engineering tissue scaffolds significantly affect cell activity and scaffold stability.
Shengmao Lin, Nashaita Y. Patrawalla, Yingnan Zhai, Pengfei Dong, Vipuil Kishore, Linxia Gu   +5 more
doaj   +1 more source

Application of Tannic Acid and Fe³⁺ Crosslinking-Enhanced Pectin Films for Passion Fruit Preservation

Foods, 2023
In this work, the role of tannic acid (TA) and Fe3+ in crosslinking pectin (PE) to enhance its physicochemical properties was investigated. Specifically, PE/TA/Fe3+ composite films were prepared using the solution casting method, and the UV-blocking ...
Jun Yang, Wenjin Cai, Mohammad Rizwan Khan, Naushad Ahmad, Zhengke Zhang, Lanhuan Meng, Wanli Zhang   +6 more
doaj   +1 more source

Synthesis of Crosslinkable Alkali-Soluble Resins and Self-Crosslinking Polyacrylic Latexes

Molecules
In the field of water-based inks, the use of alkali-soluble resins (ASRs) as polymeric surfactants for synthesizing polyacrylate latexes has become a mainstream method. This study first designed and prepared crosslinkable ASRs with a diacetone acrylamide
Min Li, Yansen Wang, Jun Ye, Longhai Guo, Haiqiao Wang   +4 more
doaj   +1 more source

The Effects of Citric Acid Crosslinking on Fabrication and Characterization of Gelatin/Curcumin-Based Electrospun Antioxidant Nanofibers

Antioxidants, 2023
Nanofibers, produced through the novel method of electrospinning, have a high ratio of surface area to volume, which allows them to have different optical, electrical, thermal, and mechanical properties than macroscale materials.
Reem Hasan, Gulum Sumnu, Serpil Sahin, Emel Oz, Fatih Oz   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Optical Correction of Keratoconus with a Scleral Gas-Permeable Lenses

Oftalʹmologiâ, 2019
The optical properties of the cornea are determined by its ability to refract and transmit light. Keratoconus changes cornea’s shape, the surface of the cornea becomes irregular, which leads to a violation of light refraction and the occurrence of ...
A. V. Myagkov, Yu. B. Slonimskiy, E. V. Belousova, T. S. Mitichkina, L. R. Bunyatova   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Tough Materials Through Ionic Interactions

Frontiers in Chemistry, 2021
This article introduces butyl acrylate-based materials that are toughened with dynamic crosslinkers. These dynamic crosslinkers are salts where both the anion and cation polymerize.
Linda Salminen, Erno Karjalainen, Vladimir Aseyev, Heikki Tenhu   +3 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source