Results 41 to 50 of about 203,473 (308)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
UV cross-linked polyvinylpyrrolidone electrospun fibres as antibacterial surfaces
Many bacteria become progressively more resistant to antibiotics and it remains a challenging task to control their overall levels. Polymers combined with active biomolecules come to the forefront for the design of antibacterial materials that can ...
Barbara M. Maciejewska +9 more
doaj +1 more source
Development of in situ bioprinting: A mini review
Bioprinting has rapidly progressed over the past decade. One branch of bioprinting known as in situ bioprinting has benefitted considerably from innovations in biofabrication.
Aidan MacAdam +7 more
doaj +1 more source
Effect of 1,2,3-Trichloropropane as Tri-Functional Monomer on Thermophysical Properties of Poly(ethylene tetrasulfide) [PDF]
In this study, the effect of 1,2,3-trichloropropane (TCP) as trifunctional monomer on thermophysical properties of synthesized poly(ethylene tetrasulfide) (PETS) is investigated. To this end, different amounts of TCP (0-40 mol.
Mina Amangah +2 more
doaj +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Innovations in Corneal Crosslinking.
PURPOSE Corneal Crosslinking (CXL) strengthens the keratoconus cornea and prevents further disease progression. Modified crosslinking protocols and different riboflavin solutions have been proposed to optimize the procedure and improve treatment ...
Borgardts, Klara +5 more
core +1 more source
To combat climate change, one approach is to manufacture products from biomass-fungi composite materials instead of petroleum-based plastics. These products can be used in packaging, furniture, and construction industries.
Al Mazedur Rahman +6 more
doaj +1 more source
Improving the rheological properties of 18% wheat flour as affected by transglutaminase enzyme [PDF]
Enzymes are useful to modify wheat proteins to preserve the gas better and to correct the rheological properties of the dough of weak flour and bread.
Rahim Rahebi Bardi +2 more
doaj
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Alexandru Fofiu,1,2 Robert G Tripon,3 Tiberiu Băţagă,4 Traian V Chirilă2,5– 8 1Department of Orthopedics-Traumatology, Emergency County Hospital Bistriţa, Bistriţa Năsăud, Romania; 2School of ...
Băţagă T +3 more
core

