Results 41 to 50 of about 203,473 (308)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

UV cross-linked polyvinylpyrrolidone electrospun fibres as antibacterial surfaces

open access: yesScience and Technology of Advanced Materials, 2019
Many bacteria become progressively more resistant to antibiotics and it remains a challenging task to control their overall levels. Polymers combined with active biomolecules come to the forefront for the design of antibacterial materials that can ...
Barbara M. Maciejewska   +9 more
doaj   +1 more source

Development of in situ bioprinting: A mini review

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Bioprinting has rapidly progressed over the past decade. One branch of bioprinting known as in situ bioprinting has benefitted considerably from innovations in biofabrication.
Aidan MacAdam   +7 more
doaj   +1 more source

Effect of 1,2,3-Trichloropropane as Tri-Functional Monomer on Thermophysical Properties of Poly(ethylene tetrasulfide) [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2020
In this study, the effect of 1,2,3-trichloropropane (TCP) as trifunctional monomer on thermophysical properties of synthesized poly(ethylene tetrasulfide) (PETS) is investigated. To this end, different amounts of TCP (0-40 mol.
Mina Amangah   +2 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Innovations in Corneal Crosslinking.

open access: yes, 2023
PURPOSE Corneal Crosslinking (CXL) strengthens the keratoconus cornea and prevents further disease progression. Modified crosslinking protocols and different riboflavin solutions have been proposed to optimize the procedure and improve treatment ...
Borgardts, Klara   +5 more
core   +1 more source

Effects of Sodium Alginate and Calcium Chloride on Fungal Growth and Viability in Biomass-Fungi Composite Materials Used for 3D Printing

open access: yesBiomimetics
To combat climate change, one approach is to manufacture products from biomass-fungi composite materials instead of petroleum-based plastics. These products can be used in packaging, furniture, and construction industries.
Al Mazedur Rahman   +6 more
doaj   +1 more source

Improving the rheological properties of 18% wheat flour as affected by transglutaminase enzyme [PDF]

open access: yesJournal of Food and Bioprocess Engineering, 2020
Enzymes are useful to modify wheat proteins to preserve the gas better and to correct the rheological properties of the dough of weak flour and bread.
Rahim Rahebi Bardi   +2 more
doaj  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Exogenous Crosslinking of Tendons as a Strategy for Mechanical Augmentation and Repair: A Narrative Review

open access: yes, 2023
Alexandru Fofiu,1,2 Robert G Tripon,3 Tiberiu Băţagă,4 Traian V Chirilă2,5– 8 1Department of Orthopedics-Traumatology, Emergency County Hospital Bistriţa, Bistriţa Năsăud, Romania; 2School of ...
Băţagă T   +3 more
core  

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