Results 41 to 50 of about 197,806 (310)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The Science and Clinical Evolution of Corneal Cross-Linking: Mechanism of Action, Ultra-Structural Changes, Clinical Indications, and Emerging Treatment Strategies

Ophthalmology and Therapy
Keratoconus is the most common corneal ectatic disorder worldwide. Typically manifesting in adolescence, it imposes a substantial burden on quality of life and, if untreated, may progress to advanced stages requiring corneal transplantation.
Cosimo Mazzotta, Marco Lombardo, Alessandro Avitabile, Giovanni Alessio, Davide Borroni, Francesco D’Oria   +5 more
doaj   +1 more source

UV cross-linked polyvinylpyrrolidone electrospun fibres as antibacterial surfaces

Science and Technology of Advanced Materials, 2019
Many bacteria become progressively more resistant to antibiotics and it remains a challenging task to control their overall levels. Polymers combined with active biomolecules come to the forefront for the design of antibacterial materials that can ...
Barbara M. Maciejewska, Jacek K. Wychowaniec, Marta Woźniak-Budych, Łukasz Popenda, Alicja Warowicka, Klaudia Golba, Jagoda Litowczenko, Zbigniew Fojud, Beata Wereszczyńska, Stefan Jurga   +9 more
doaj   +1 more source

Development of in situ bioprinting: A mini review

Frontiers in Bioengineering and Biotechnology, 2022
Bioprinting has rapidly progressed over the past decade. One branch of bioprinting known as in situ bioprinting has benefitted considerably from innovations in biofabrication.
Aidan MacAdam, Emaan Chaudry, Christopher D. McTiernan, David Cortes, Erik J. Suuronen, Erik J. Suuronen, Emilio I. Alarcon, Emilio I. Alarcon   +7 more
doaj   +1 more source

Effect of 1,2,3-Trichloropropane as Tri-Functional Monomer on Thermophysical Properties of Poly(ethylene tetrasulfide) [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2020
In this study, the effect of 1,2,3-trichloropropane (TCP) as trifunctional monomer on thermophysical properties of synthesized poly(ethylene tetrasulfide) (PETS) is investigated. To this end, different amounts of TCP (0-40 mol.
Mina Amangah, Mehdi Salami Kalajahi, Hossein Roghani-Mamaqani   +2 more
doaj   +1 more source

Effects of Crosslinking Methods on Network Structure and Enzymatic Degradation of Methacrylate-Functionalized Chitosan Hydrogel [PDF]

, 2018
Polysaccharides, such as hyaluronic acid, alginate, or chitosan, can be modified by addition of reactive functional groups to enable chemical crosslinking.
Juhong Ahn (6067943), Juhong, Ahn, Jungju Ryu (6067958), Kwangho Song (6067964), Jungwook Kim (6067967), Jungwook, Kim, Kwangho, Song, Jungju, Ryu   +7 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Effects of Sodium Alginate and Calcium Chloride on Fungal Growth and Viability in Biomass-Fungi Composite Materials Used for 3D Printing

Biomimetics
To combat climate change, one approach is to manufacture products from biomass-fungi composite materials instead of petroleum-based plastics. These products can be used in packaging, furniture, and construction industries.
Al Mazedur Rahman, Caleb Oliver Bedsole, Yeasir Mohammad Akib, Jillian Hamilton, Taieba Tuba Rahman, Brian D. Shaw, Zhijian Pei   +6 more
doaj   +1 more source

Improving the rheological properties of 18% wheat flour as affected by transglutaminase enzyme [PDF]

Journal of Food and Bioprocess Engineering, 2020
Enzymes are useful to modify wheat proteins to preserve the gas better and to correct the rheological properties of the dough of weak flour and bread.
Rahim Rahebi Bardi, Mahsa Tabari, Hamid Tavakolipor   +2 more
doaj  

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source