Results 61 to 70 of about 404,496 (337)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Optimum sol viscosity for stable electrospinning of silica nanofibres [PDF]
, 2013 Silica nanofibres have, due to their excellent properties, promising characteristics for multiple applications such as filtration, composites, catalysis, etc. Silica nanofibres can be obtained by combining electrospinning and the sol–gel process.
De Buysser, Klaartje +4 more
core +1 more source
Advances in Materials, 2016 The preparation of highly efficient perovskite nanocrystal light-emitting diodes is shown. A new trimethylaluminum vapor-based crosslinking method to render the nanocrystal films insoluble is applied. The resulting near-complete nanocrystal film coverage,
Guangru Li +11 more
semanticscholar +1 more source
Macromolecular Bioscience, 2020 Synthetically modified proteins, such as gelatin methacryloyl (GelMA), are growing in popularity for bioprinting and biofabrication. GelMA is a photocurable macromer that can rapidly form hydrogels, while also presenting bioactive peptide sequences for ...
Ashlyn T. Young +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Optical Correction of Keratoconus with a Scleral Gas-Permeable Lenses
Oftalʹmologiâ, 2019 The optical properties of the cornea are determined by its ability to refract and transmit light. Keratoconus changes cornea’s shape, the surface of the cornea becomes irregular, which leads to a violation of light refraction and the occurrence of ...
A. V. Myagkov +4 more
doaj +1 more source
RNA Crosslinking Methods [PDF]
, 2009 RNA-RNA crosslinking provides a rapid means of obtaining evidence for the proximity of functional groups in structurally complex RNAs and ribonucleoproteins. Such evidence can be used to provide a physical context for interpreting structural information from other biochemical and biophysical methods and for the design of further experiments.
Michael E, Harris, Eric L, Christian
openaire +2 more sources
Crosslinking in parallel [PDF]
, 1992 A crosslink is a double link established between the two entries of an edge in an adjacency list representation of a graph. Crosslinks play important roles in several parallel algorithms as they provide constant time access between the two entries of an ...
Asuri, Hari S.
core
Gating mechanism of elongating β-ketoacyl-ACP synthases. [PDF]
, 2020 Carbon-carbon bond forming reactions are essential transformations in natural product biosynthesis. During de novo fatty acid and polyketide biosynthesis, β-ketoacyl-acyl carrier protein (ACP) synthases (KS), catalyze this process via a decarboxylative ...
Bartholow, Thomas G +9 more
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source