Results 181 to 190 of about 3,099 (216)

Immunosuppresive role of principal toxin (crotoxin) of Crotalus durissus terrificus venom

Toxicon, 2004
The composition of the crotalic venom and the immunochemistry and/or pathophysiological characterization and main components were well studied. However, few studies have been carried out to investigate the effect of toxins of this venom on the development of the immune response.
A, Rangel-Santos, C, Lima, M, Lopes-Ferreira, D F, Cardoso   +3 more
openaire   +2 more sources

Panicolytic-like effect of µ1-opioid receptor blockade in the inferior colliculus of prey threatened by Crotalus durissus terrificus pit vipers

Journal of Psychopharmacology, 2019
Background: The endogenous opioid peptide system has been implicated in the neural modulation of fear and anxiety organised by the dorsal midbrain.
F. Calvo, R. C. Almada, Tayllon dos Anjos-Garcia, Luiz Luciano Falconi- Sobrinho, T. Paschoalin-Maurin, Guilherme Bazaglia-de-Sousa, P. Medeiros, Juliana Almeida da Silva, B. Lobão-Soares, N. Coimbra   +9 more
semanticscholar   +1 more source

Inhibitory potential of Crotalus durissus terrificus venom on measles virus growth

Toxicon, 2003
This paper presents the antiviral activity found in a snake with Crotalus durissus terrificus venom (Cdt), studied by use of microplate inhibition assay, using measles virus (MV). Cdt at concentrations below 100 microg/ml showed no cytotoxicity for Vero cells. This study shows the optimal conditions for cell treatment and infection.
Vera L, Petricevich, Ronaldo Z, Mendonça   +1 more
openaire   +2 more sources

In-Depth Venome of the Brazilian Rattlesnake Crotalus durissus terrificus: An Integrative Approach Combining Its Venom Gland Transcriptome and Venom Proteome.

Journal of Proteome Research, 2018
Snake venoms are complex mixtures mainly composed of proteins and small peptides. Crotoxin is one of the most studied components from Crotalus venoms, but many other components are less known due to their low abundance.
G. Wiezel, P. Y. T. Shibao, C. Cologna, Romualdo Morandi Filho, C. Ueira-Vieira, E. De Pauw, L. Quinton, E. Arantes   +7 more
semanticscholar   +1 more source

WITHDRAWN: Microvesicles in the venom of Crotalus durissus terrificus (Serpentes, Viperidae)

Toxicon, 2006
The Publisher regrets that this article was an accidental duplication of an article that has already been published in Toxicon, 49 (2007) 106-110, . The duplicate article has therefore been withdrawn.
Sylvia Mendes, Carneiro, Wilson, Fernandes, Savio Stefanini, Sant'anna, Norma, Yamanouye   +3 more
openaire   +2 more sources

Effect of Isolated Proteins from Crotalus Durissus Terrificus Venom on Leishmania (Leishmania) Amazonensis-Infected Macrophages.

Protein Peptide Letters, 2020
BACKGROUND Cutaneous and mucocutaneous leishmaniasis are parasitic diseases characterized by skin manifestations. In Brazil, Leishmania (Leishmania) amazonensis is one of the etiological agents of cutaneous leishmaniasis.
Simone Katz, C. Barbiéri, F. Soler, A. Soares, M. Chavantes, S. Zamuner   +5 more
semanticscholar   +1 more source

A comparative study of biological activities of crotoxin and CB fraction of venoms from Crotalus durissus terrificus, Crotalus durissus cascavella and Crotalus durissus collilineatus

Toxicon, 2004
In Brazil, the Crotalus durissus terrificus subspecie is the most studied, particularly concerning its crotoxin. Crotoxin is the major toxic component of the South American rattlesnake Crotalus durissus venom. It is composed of two different subunits, CA called crotapotin and CB weakly toxic phospholipase A2 with high enzymatic activity. In this paper,
A, Rangel-Santos, E C, Dos-Santos, M, Lopes-Ferreira, C, Lima, D F, Cardoso, I, Mota   +5 more
openaire   +2 more sources

Identification of crotasin, a crotamine-related gene of Crotalus durissus terrificus

Toxicon, 2004
Crotamine is a cationic peptide (4.9 kDa, pI 9.5) of South American rattlesnake, Crotalus durissus terrificus' venom. Its presence varies according to the subspecies or the geographical locality of a given species. At the genomic level, we observed the presence of 1.8 kb gene, Crt-p1, in crotamine-positive specimens and its absence in crotamine ...
G, Rádis-Baptista, T, Kubo, N, Oguiura, A R B, Prieto da Silva, M A F, Hayashi, E B, Oliveira, T, Yamane   +6 more
openaire   +2 more sources

Snake Venomic of Crotalus durissus terrificus—Correlation with Pharmacological Activities

Journal of Proteome Research, 2010
The snake venomic of Crotalus durissus terrificus was analyzed by 2-D and 1-D electrophoresis and subsequent MS/MS and enzymatic assays. The venomic of the South American rattlesnake comprises toxins from seven protein families: phospholipases A(2), serine proteinases, ecto-5'-nucleotidases, metalloproteinases, nerve growth factors, phosphodiesterases,
Georgieva, Dessislava, Oehler, Michaela, Seifert, Jana, von Bergen, Martin, Arni, Raghuvir K., Genov, Nicolay, Betzel, Christian   +6 more
openaire   +3 more sources

Purification of gyroxin from a South American rattlesnake (Crotalus durissus terrificus) venom

Toxicon, 1980
Abstract Gyroxin, a non-lethal toxin from Crotalus durissus terrificus venom was isolated by a procedure involving two chromatographies on Sephadex G-75 at pH 4·0; ion exchange chromatography on CM-Sephadex C-50 at pH 3·5 and chromatography on Sephadex G-75 at pH 4·0.
C, Seki, J C, Vidal, A, Barrio
openaire   +2 more sources