Results 221 to 230 of about 214,613 (295)

Palaeolandscape reconstruction of a shallow coastal embayment in Kattegat, Denmark—influence of sea‐level changes during the latest Pleistocene and Holocene

Boreas, EarlyView.
We analyse the geological processes of a coastal embayment in the Kattegat. Using high‐resolution seismic data and sediment cores, we describe a geological evolution from glacial to shallow marine stages with a variety of preserved facies from different depositional settings, including glacio‐lacustrine, telmatic, limnic and coastal environments.
Katrine Juul Andresen, Lars Ole Boldreel, Ole Bennike, Christof Pearce, Mikkel Fruergaard, Verner Brandbyge Ernstsen, Aart Kroon, Nicole Rita Posth, Marit‐Solveig Seidenkrantz   +8 more
wiley   +1 more source

Psyche Mission Description and Design Rationale. [PDF]

Space Sci Rev
Polanskey CA, Elkins-Tanton LT, Bell JF, Alonge EK, Bairstow SH, Binzel RP, Biswas A, Bury L, Cisneros E, Han D, Jun I, Klipstein WM, Lawrence DJ, McCoy TJ, Mastrodemos N, Merayo JMG, Noble SK, Oh DY, Oran R, Ortega CA, Park RS, Peplowski PN, Prettyman TH, Rayman MD, Ream JB, Roatsch T, Weise TM, Wenkert DD, Weiss BP, Zuber MT.   +29 more
europepmc   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche, Tobias Litzenburger, Dorothy De Sousa, Reinhard Sailer, Ewald Benediktus, Denis Delic, Fabian Müller, Meike Müller, Jens M. Hohlfeld   +8 more
wiley   +1 more source

Fenofibrate potentiates the therapeutic efficacy of EZH2 inhibitors on melanoma via TRIM21‐ and OTUD4‐mediated EZH2 ubiquitination

British Journal of Pharmacology, EarlyView.
Background and Purpose EZH2 (enhancer of zeste homologue 2) inhibitors are an emerging class of drugs that target epigenetic regulation. However, their efficacy in solid tumours has been limited, partly due to drug‐induced upregulation of fatty acid synthesis.
Rui Cheng, Yuanjun Tang, Xuedi Cao, Xiaotong Yu, Zhanya Huang, Yunyun Guo, Renjing Jin, Yan Wang, Yang Liu, Lixiang Xue, Yuqing Wang   +10 more
wiley   +1 more source

Microfibers Accumulation within a Mediterranean Submesoscale Cyclone. [PDF]

Environ Sci Technol
Testa G, Suaria G, Paluselli A, La Ragione S, Gambale M, Berta M, Rivera LA, Mahadevan A, Middleton L, Falcieri FM, Aliani S, Griffa A.   +11 more
europepmc   +1 more source

Children of Divorced Parents—The Limitations of One‐Size‐Fits‐All Interventions

Child &Family Social Work, EarlyView.
ABSTRACT The political agenda of the Danish School Reform in 2014 provides a heightened awareness of pupils' mental health–including children of divorced parents. The primary focus is to support children's emotion management, and in that regard, conversation groups are offered to children experiencing divorce.
Pernelle Rose Hansen
wiley   +1 more source

Photochemical Synthesis of Ynones from Aryl Aldehydes and Sulfone-Based Alkynes. [PDF]

J Org Chem
Cruise A, Baumann M.
europepmc   +1 more source

What Linked Data Can Tell Us About the Increasing Numbers of Children Entering Public Care

Child &Family Social Work, EarlyView.
ABSTRACT The number of children in public care in Wales, UK, rose from the mid‐1990s to 2021. It is unclear if this change was related to increases in risk factors in parents, changes in the impact of risk factors, or changing policies and practices.
Nell Warner, Donald Forrester, Jonathan Scourfield, Rebecca Cannings‐John, Ann John   +4 more
wiley   +1 more source

Gradient Boosting for the Spectral Super-Resolution of Ocean Color Sensor Data. [PDF]

Sensors (Basel)
Slocum B, Jolliff J, Ladner S, Lawson A, Lewis MD, McCarthy S.   +5 more
europepmc   +1 more source

Changes in Peri‐Implant Soft Tissue Dimensions Following Soft Tissue Contour Augmentation: A 3‐Year Follow‐Up of a Multi‐Center RCT

Clinical Oral Implants Research, EarlyView.
ABSTRACT Aim To assess 3‐year changes of peri‐implant tissues following previous soft tissue (volume) augmentation (STA) with a volume‐stable collagen matrix (VCMX) or connective tissue (SCTG) at single‐implant restorations. Material and Methods In a non‐interventional follow‐up observation, peri‐implant tissues were evaluated with regard to buccal ...
Karin Jepsen, Søren Jepsen, Christoph H. F. Hämmerle, Leonardo Mancini, Franz J. Strauss, Malin Strasdin, Stefan Hicklin, Mariano Sanz, Ignacio Sanz‐Martin, Daniel S. Thoma, Irena Sailer   +10 more
wiley   +1 more source