Results 251 to 260 of about 43,819,564 (282)

Structural basis for epitopes sharing between group 1 allergens of cedar pollen, Jun a 1 and Cry j 1

Journal of Allergy and Clinical Immunology, 2004
Abstract Rationale Resolution of the 3D-structures and IgE epitopes of allergens may identify common or conserved features important for the biological activity of allergens. Methods Purified Jun a 1 was crystallized using the hanging-drop vapour-diffusion method at 277 K.
T. Midoro-Horiuti, D. Liu, M.A. White, E.W. Czerwinski, V. Mathura, C.H. Schein, W. Braun, M. Watanabe, T. Oka, A. Togawa, E.G. Brooks, R.M. Goldblum   +11 more
openaire   +1 more source

Pollen-Specific Expression of the Gene for an Allergen, Cry j 1, in Cryptomeria japonica

Journal of Forest Research, 1998
A cDNA fragment for an allergen, Cry j 1 in sugi (Cryptomeria japonica D. Don) was generated by the reverse transcriptase-polymerase chain reaction. Using this cDNA fragment, we determined the number of copies of theCry j 1 gene in the sugi genome and the organ-specific expression of theCry j 1 gene in sugi trees.
Yunqiu Wang, Yuzuru Mukai, Mitsue Fukui, Norihiro Futamura, Akinori Nagao, Kenji Shinohara   +5 more
openaire   +1 more source

Roles of carbohydrates on Cry j 1, the major allergen of Japanese cedar pollen, in specific T-cell responses

Journal of Allergy and Clinical Immunology, 2001
Carbohydrates expressed on allergens are known to be important for allergenicity. However, little is known about whether the carbohydrates drive the T(H)2 response.We sought to determine a role for carbohydrates expressed on Cry j 1, which is the major allergen of Cryptomeria japonica pollen and causes the most prevalent pollinosis in Japan, in in ...
M, Okano, K, Kino, T, Takishita, H, Hattori, T, Ogawa, T, Yoshino, M, Yokoyama, K, Nishizaki   +7 more
openaire   +2 more sources

Peptide Specificity, HLA Class II Restriction, and T–Cell Subsets of the T–Cell Clones Specific to Either Cry j 1 or Cry j 2, the Major Allergens of Japanese Cedar (Cryptomeria japonica) Pollen

International Archives of Allergy and Immunology, 1999
<b>Background:</b> Cry j 1 and Cry j 2 are thought to be the major allergens of Japanese cedar pollen. HLA class II types capable of presenting T–cell epitopes in both allergens and their role in induction of T–cell subsets are not well known.
T, Sone, K, Morikubo, K, Shimizu, N, Komiyama, H, Tsunoo, K, Kino   +5 more
openaire   +2 more sources

Identification of peptides containing T-cell epitopes of Japanese cedar (Cryptomeria japonica) pollen allergen (Cry j 1) in dogs

Veterinary Immunology and Immunopathology, 2004
Japanese cedar (Cryptomeria japonica, CJ) pollen has been known to cause atopic dermatitis in dogs in Japan. However, since the mechanism of the CJ antigen recognition is not well understood in dogs, it is difficult to develop effective immunotherapy for atopic dermatitis caused by sensitization to CJ pollen. In order to aim at development of a peptide
K, Masuda, M, Sakaguchi, S, Saito, H, Yasueda, S, Iwabuchi, T, Tsukui, N, Hayashi, Y, Nakao, K, Kurata, S, Maeda, K, Ohno, H, Tsujimoto   +11 more
openaire   +2 more sources

Cry j 1 isoforms derived from Cryptomeria japonica trees have different binding properties to monoclonal antibodies

Clinical & Experimental Allergy, 2004
SummaryBackground We identified five Cryptomeria japonica trees producing Cry j 1 isoforms that cannot be detected in a sandwich ELISA using two monoclonal antibodies, J1B01 and J1B07, suggesting that the binding affinity of these isoforms for both monoclonal antibodies is low.Objectives The binding properties of the Cry j 1 isoforms ...
Y, Goto, T, Kondo, T, Ide, H, Yasueda, N, Kuramoto, K, Yamamoto   +5 more
openaire   +2 more sources

[Development of the simple method for measurement the content of Cry j 1 in the air by latex agglutination test].

Arerugi = [Allergy], 2006
In order to develop an easy method for measure the airborne C. japonica pollen allergen (Cry j 1) without any utensils or a special apparatus, we examined latex agglutination test for the purpose.The latex beads were reacted with the anti-Cry j 1 polyclonal antibody, and the beads were blocked with bovine serum albumin (sensitized beads).
Yuichi, Takahashi, Masaaki, Aoyama
openaire   +1 more source

Antigenic analysis of Cryptomeria japonica and Chamaecyparis obtusa using anti-Cry j 1 monoclonal antibodies.

Acta oto-laryngologica. Supplementum, 1997
In Japan, pollen of Cryptomeria japonica and Chamaecyparis obtusa are a yearly source of distress for many people suffering seasonally from allergic rhinitis. To study common epitopes shared by the two species, two monoclonal antibodies (moAbs) were raised against Cry j 1, which is the most predominant allergen in C. japonica.
M, Suzuki, M, Ito, H, Ito, S, Baba, I, Takagi, H, Yasueda, N, Ohta   +6 more
openaire   +1 more source

Monoclonal Antibody and IgE Binding to Purified Natural Cry j 1

Journal of Allergy and Clinical Immunology, 2011
S. Wünschmann, B.P. Brooks, A.E. Koid, K. Ichikawa, M.D. Chapman   +4 more
openaire   +1 more source

A review of infant cry analysis and classification

Eurasip Journal on Audio, Speech, and Music Processing, 2021
Yi Pan, Chunyan Ji
exaly