Results 41 to 50 of about 43,819,564 (282)

IgE responses to multiple allergen components among school-aged children in a general population birth cohort in Tokyo

World Allergy Organization Journal, 2020
Background: Response patterns to allergen components among Japanese children have not been studied extensively. Objective: Our aim was to examine the differences in sensitization patterns at ages 5 years and 9 years to identify longitudinal changes in ...
Kiwako Yamamoto-Hanada, Magnus P. Borres, Magnus K. Åberg, Limin Yang, Tatsuki Fukuie, Masami Narita, Hirohisa Saito, Yukihiro Ohya   +7 more
doaj   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

Reduction of Cry j 1 allergenicity by nano-sized electrostatic atomized water particles (NEAWPs) in human bronchial epithelium and dendritic cells

International Journal of Air-Conditioning and Refrigeration
Japanese cedar pollen (Cryptomeria japonica) is a major cause of seasonal allergic rhinitis in Japan, and Cry j 1 has been identified as its principal allergen.
Sasa Iwamatsu, Yuta Kaga, Yasuhiro Komura, Yohei Ishigami, Tomoki Fukuyama   +4 more
doaj   +1 more source

Efficacy of oral immunotherapy with a rice-based edible vaccine containing hypoallergenic Japanese cedar pollen allergens for treatment of established allergic conjunctivitis in mice

Allergology International, 2018
Background: We have previously shown that prophylactic oral administration of transgenic rice seeds expressing hypoallergenic modified antigens suppressed the development of allergic conjunctivitis induced by Japanese cedar pollen.
Ken Fukuda, Waka Ishida, Yosuke Harada, Yuhya Wakasa, Hidenori Takagi, Fumio Takaiwa, Atsuki Fukushima   +6 more
doaj   +1 more source

A new murine model of allergic rhinitis by repeated intranasal Cry j 1 challenge

Biomedical Research, 2008
To evaluate the long-lasting effects of new therapeutic approaches to allergies, we established a new model of allergic rhinitis by repeated challenges with intranasal Cry j 1, a common Japanese cedar (Cryptomeria japonica) pollen allergen, in B10.S mice. We sensitized B10.S mice subcutaneously with Cry j 1/alum three times at 1-week intervals.
TSUNEMATSU, Masako, YAMAJI, Taketo, KOZUTSUMI, Daisuke, MURAKAMI, Rika, NAGAI, Hiroichi, KINO, Kohsuke   +5 more
openaire   +3 more sources

Enviromics and Abiotic Enviromics: Enhancing Stress Biology and Plant Resilience Breeding

Advanced Science, EarlyView.
Environmental stressors are captured through high‐throughput envirotyping and integrated into an enviromic framework with genomic, transcriptomic, phenomic, and environmental data. AI/ML models enable prediction and guide marker‐assisted selection, genomic selection, genome editing, and gene pyramiding toward improved abiotic stress tolerance, yield ...
Guangchao Sun, Jose Luis Araus, James C. Schnable, Jie Xu, Henry T. Nguyen, Yunbi Xu, Yanli Lu   +6 more
wiley   +1 more source

Structural and Stability Analysis of GRP Family Allergens Pru p 7 and Cry j 7, Which Cause Pollen and Food Allergy Syndrome

Biomolecules
Cry j 7 is a 7 kDa cysteine-rich gibberellin regulatory protein (GRP) with six disulfide bonds. It was isolated from Japanese cedar as the pollen allergen in this study.
Jingkang Zheng, Hiroyuki Kumeta, Yasuhiro Kumaki, Tomona Iizuka, Ichiho Yoshikawa, Ami Hanaoka, Tomoyasu Aizawa   +6 more
doaj   +1 more source

Therapeutic Effects of β1, 4 Mannobiose in a Balb/c Mouse Model of Intranasally-Induced Pollen Allergy

Allergology International, 2013
Background: Nutritional prebiotic supplementation represents an attractive approach for interventions of allergy. In this study, the potential therapeutic effect of β-1, 4 mannobiose (MNB) in a murine model of cedar polli- nosis was investigated. Methods:
Chengbo Yang, Prithy Rupa, Hiroyuki Kanatani, Akihiro Nakamura, Masahisa Ibuki, Yoshinori Mine   +5 more
doaj   +1 more source

Multimodal Learning with Rashomon Analysis for Battery Discharge Capacity Prediction

Advanced Intelligent Discovery, EarlyView.
Multimodal fusion integrates composition, crystal‐structure, and radial‐distribution descriptors to predict battery discharge capacity. Rashomon analysis across near‐optimal models reveals that explanatory variation is structured rather than arbitrary, separating stable mechanistic signals from model‐contingent attributions and providing a more ...
Jue Gong, Lejia Wang, Tianqing Zhu, Keith Butler, Sichao Li   +4 more
wiley   +1 more source

Border harm and affective injustice: The politics of anger at the Melilla border, Spain

American Journal of Community Psychology, EarlyView.
Abstract This article examines protests in a detention center in Melilla, Spain—a site where structural violence intersects with the everyday harms of confinement. Adopting a justice and dignity‐centered perspective, we analyze grassroots forms of resistance emerging at the border. The study focuses on the protests of Tunisian migrants and explores the
Corina Tulbure
wiley   +1 more source