Results 21 to 30 of about 43,819,564 (282)

CRTH2 Plays an Essential Role in the Pathophysiology of Cry j 1-Induced Pollinosis in Mice [PDF]

The Journal of Immunology, 2008
Abstract PGD2 is the major prostanoid produced during the acute phase of allergic reactions. Two PGD2 receptors have been isolated, DP and CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), but whether they participate in the pathophysiology of allergic diseases remains unclear.
Rie, Nomiya, Mitsuhiro, Okano, Tazuko, Fujiwara, Megumi, Maeda, Yoshinobu, Kimura, Kosuke, Kino, Minehiko, Yokoyama, Hiroyuki, Hirai, Kinya, Nagata, Toshifumi, Hara, Kazunori, Nishizaki, Masataka, Nakamura   +11 more
openaire   +2 more sources

Bacillus thuringiensis Isolated from Flour Mill Soil And Its Toxicity Against Culex And Aedes Larvae

Journal of Microbiology and Infectious Diseases, 2021
Objectives: Entomotoxic microorganisms are becoming very effective as biocontrol agents in alternative to chemical formulations. This study aimed to evaluate isolation, characterization, and determination of the larvicidal activity of Bacillus ...
Majekodunmi Racheal Adedayo, Azeezat Ayodeji Uthman   +1 more
doaj   +1 more source

Analysis of the canine IgE-binding epitope on the major allergen (Cry j 1) of Japanese cedar pollen with anti-Cry j 1 monoclonal antibodies

Veterinary Immunology and Immunopathology, 2001
In our previous study [Immunology 91 (1997) 161] using monoclonal antibodies (mAbs) specific to Cry j 1, a major allergen in Japanese cedar (Cryptomeria japonica) pollen, we identified five independent epitopes (EP-1-EP-5) on the molecule and found that EP-1 and EP-5 are the predominant allergic epitopes for humans and monkeys, respectively.
M, Sakaguchi, K, Masuda, M, Toda, S, Inouye, H, Yasueda, Y, Taniguchi, T, Nagoya, D J, DeBoer, H, Tsujimoto   +8 more
openaire   +5 more sources

Identification of Cha o 3 homolog Cry j 4 from Cryptomeria japonica (Japanese cedar) pollen: Limitation of the present Japanese cedar–specific ASIT

Allergology International, 2018
Background: About one-third of the Japanese population suffers from Japanese cedar pollinosis, which is frequently accompanied by Japanese cypress pollinosis. Recently, a novel major Japanese cypress pollen allergen, Cha o 3, was discovered.
Toshihiro Osada, Yuki Tanaka, Akira Yamada, Eiji Sasaki, Teruhiro Utsugi   +4 more
doaj   +1 more source

Evaluation of basophil activation caused by transgenic rice seeds expressing whole T cell epitopes of the major Japanese cedar pollen allergens

Clinical and Translational Allergy, 2019
Background Japanese cedar (JC) pollinosis is a serious type I allergic disease in Japan. Although subcutaneous immunotherapy and sublingual immunotherapy have been applied to treat JC pollinosis, high doses of allergens may cause IgE-mediated allergic ...
Shinya Takaishi, Saburo Saito, Minori Kamada, Nobuyoshi Otori, Hiromi Kojima, Kenjiro Ozawa, Fumio Takaiwa   +6 more
doaj   +1 more source

Concentrated protein body product derived from rice endosperm as an oral tolerogen for allergen-specific immunotherapy--a new mucosal vaccine formulation against Japanese cedar pollen allergy.

PLoS ONE, 2015
The endoplasmic reticulum-derived type-I protein body (PB-I) from rice endosperm cells is an ideal candidate formulation for the oral delivery of bioencapsulated peptides as tolerogens for allergen-specific immunotherapy.
Yuhya Wakasa, Hidenori Takagi, Nobumasa Watanabe, Noriko Kitamura, Yoshihiro Fujiwara, Yuko Ogo, Shimpei Hayashi, Lijun Yang, Masaru Ohta, Wai Wai Thet Tin, Kenji Sekikawa, Makoto Takano, Kenjirou Ozawa, Takachika Hiroi, Fumio Takaiwa   +14 more
doaj   +1 more source

[Development of super-sensitive radical immunoassay for Cry j 1].

Arerugi = [Allergy], 2004
We have been developed super-sensitive method of Cry j 1 measurement by ESR radical immunoassay using p-acetamidophenol and hydroxylamine system. The detection limit for Cry j 1 was 3.5 pg/ml. It is reported that the average content of Cry j 1 in each Cryptomeria japonica pollen is about 6 pg, therefore, we can detect one grain or even less one grain ...
Aoyama, Masaaki, Takahashi, Yuichi
openaire   +2 more sources

Allergen Release Profiles of Fast-Dissolving Freeze-Dried Orodispersible Sublingual Allergy Immunotherapy Tablets

Current Therapeutic Research, 2022
: Background: Sublingual allergy immunotherapy tablets (SLIT-tablets) provide a well-tolerated and clinically efficacious treatment for allergic disease such as allergic rhinitis and allergic asthma. In SLIT, uptake of allergen by immune-competent cells
Takashi Yamamoto, PhD, Katsuyo Ohashi-Doi, PhD, Hiroki Matsuhara, BSc, Loes Verhoog, MSc, Morten Lindholm, PhD, Simon Lawton, MD, Kaare Lund, PhD   +6 more
doaj   +1 more source

Spectrum of allergens for Japanese cedar pollinosis and impact of component-resolved diagnosis on allergen-specific immunotherapy

Allergology International, 2015
The high prevalence of Japanese cedar pollinosis in Japan is associated with a negative impact on the quality of life of patients, as well as significant loss of productivity among the workforce in early spring, thus representing a serious social problem.
Takashi Fujimura, Seiji Kawamoto
doaj   +1 more source

Pollen-food allergy syndrome and component sensitization in adolescents: A Japanese population-based study.

PLoS ONE, 2021
Allergic rhino-conjunctivitis with pollen allergy has been prevalent worldwide and Pollen-food allergy syndrome (PFAS) refers to individuals with pollen allergy who develop oral allergy syndrome (OAS) on consuming fruits and vegetables. The prevalence of
Tomoyuki Kiguchi, Kiwako Yamamoto-Hanada, Mayako Saito-Abe, Miori Sato, Makoto Irahara, Hiroya Ogita, Yoshitsune Miyagi, Yusuke Inuzuka, Kenji Toyokuni, Koji Nishimura, Fumi Ishikawa, Yumiko Miyaji, Shigenori Kabashima, Tatsuki Fukuie, Masami Narita, Yukihiro Ohya   +15 more
doaj   +1 more source