Background: Although Japanese cedar (Cryptomeria japonica) pollinosis has developed into a health problem, few methods eradicate indoor allergens completely.
Tetsuya Terada +5 more
doaj +3 more sources
Recombinant Fusion Allergens, Cry j 1 and Cry j 2 from Japanese Cedar Pollen, Conjugated with Polyethylene Glycol Potentiate the Attenuation of Cry j 1-Specific IgE Production in Cry j 1-Sensitized Mice and Japanese Cedar Pollen Allergen-Sensitized Monkeys [PDF]
<b><i>Background:</i></b> Japanese cedar <i>(Cryptomeria japonica)</i> pollinosis is the most prevalent seasonal rhinitis in Japan. A standardized Japanese cedar pollen extract (CPE) containing 1.5-4.2 μg of Cry j 1 is currently the highest-concentration extract available for allergen-specific immunotherapy (SIT ...
Takashi, Fujimura +8 more
openaire +2 more sources
Characterization of the Physical Form of Allergenic Cry j 1 in the Urban Atmosphere and Determination of Cry j 1 Denaturation by Air Pollutants [PDF]
In this study, we characterized the physical form of allergenic Cry j 1 in the urban atmosphere. Through an immunofluorescence antibody method, we showed that allergenic Cry j 1 exists as fine particles (≤1.1 μm). To determine Cry j 1 concentrations and its particle size distribution, we used the ELISA method to confirm that most Cry j 1 exists as fine
Qingyue Wang +9 more
openaire +2 more sources
In allergic models, administration of rice that expresses a hybrid peptide consisting of 7 major T cell epitopes of Cry j 1 and Cry j 2 (7Crp), suppressed allergic symptoms, IgE elevation and specific T cell response to Japanese cedar pollen.To evaluate the efficacy and safety of 7Crp-expressing rice in patients with Japanese cedar pollinosis.A 24-week
YumShoji, Hashimotoi +11 more
openaire +2 more sources
The soothing effect of phlorotannins on cedar pollinosis in Cry j 1-stimulated mice
ABSTRACT The antiallergic properties of phlorotannins, algal polyphenols, have been widely reported. This study examined the soothing effect of phlorotannin concentrate (PTC) from Eisenia nipponica on cedar pollinosis in Cry j 1-stimulated mice.
Yoshimasa, Sugiura +2 more
openaire +2 more sources
Release behaviour of cryptomeria japonica pollen allergenic cry J 1 and cry J 2 in rainwater containing air pollutants [PDF]
Japanese cedar (Cryptomeria japonica) pollinosis is the most popular pollinosis in Japan. In recent years, it was reported that the most Cryptomeria japonica pollen allergenic species were scattered as fiparticles in the urban atmosphere. It is thought that allergenic fi ne particles are responsible for inducing asthma by breaking into lower ...
Q. Wang +8 more
openaire +1 more source
Genetic and Molecular Characterization of a Cryptochrome from the Filamentous Fungus Neurospora crassa [PDF]
In plants and animals, cryptochromes function as either photoreceptors or circadian clock components. We have examined the cryptochrome from the filamentous fungus Neurospora crassa and demonstrate that Neurospora cry encodes a DASH-type cryptochrome ...
Belden, William J., +23 more
core +2 more sources
Abstract Children's relationship with time in preschools is an under‐researched area. Young children rarely know how to measure time using a clock, but their experiences of time may contribute to understanding children's well‐being and debates about quality in preschools.
Kristín Dýrfjörð +3 more
wiley +1 more source
Abstract Early childhood has increasingly been acknowledged as a vital time for all children. Inclusive and quality education is part of the United Nations Sustainable Development Goals, with the further specification that all children have access to quality pre‐primary education.
Laura H. V. Wright +8 more
wiley +1 more source
Glycoform Analysis of Japanese Cedar Pollen Allergen, Cry j 1
In our previous study (Y. Kimura et al., Biosci. Biotechnol. Biochem., 69, 137-144 (2005)), we found that plant complex type N-glycans harboring Lewis a epitope are linked to the mountain cedar pollen allergen Jun a 1. Jun a 1 is a glycoprotein highly homologous with Japanese cedar pollen glycoallergen, Cry j 1.
MAEDA, Megumi +6 more
openaire +2 more sources

