Results 31 to 40 of about 43,819,564 (282)

Prophylaxis of Intranasally Induced Pollen Allergy in a BALB/C Mouse Model Using a Potential Prebiotic β-1, 4 Mannobiose

Allergology International, 2013
Background: Dietary supplementation with unique prebiotic nondigestible carbohydrates has been shown to suppress allergy. In the present study, the prophylactic efficacy of a disaccharide p-1, 4 mannobiose (MNB) in a BALB/C mouse model of intranasally ...
Chengbo Yang, Prithy Rupa, Hiroyuki Kanatani, Akihiro Nakamura, Masahisa Ibuki, Yoshinori Mine   +5 more
doaj   +1 more source

Doctors Strike During COVID-19 Pandemic in Malaysia

Voices in Bioethics, 2021
Photo by Ishan @seefromthesky on Unsplash ABSTRACT A strike to highlight the plight facing contract doctors which has been proposed has received mixed reactions from those within the profession and the public.
Jazlan Jamaluddin, Nurul Nadia Baharum, Siti Nuradliah Jamil, Mohd Azzahi Mohamed Kamel   +3 more
doaj   +1 more source

Influences of genetic and environmental factors on the concentration of the allergen Cry j 1 in sugi (Cryptomeria japonica) pollen [PDF]

Tree Physiology, 2004
Pollen from sugi (Japanese cedar, Cryptomeria japonica D. Don), a forest tree species that is widely grown in Japan, causes serious allergic disease. The major allergens from sugi pollen, Cry j 1 and Cry j 2, have been isolated and characterized. It has been reported that Cry j 1 concentration in pollen varies considerably among trees.
Yoko, Goto, Teiji, Kondo, Eiji, Hayashi, Noritsugu, Kuramoto, Makoto, Takahashi, Hiroshi, Yasueda   +5 more
openaire   +2 more sources

Polycyclic Aromatic Hydrocarbons Aggravate Antigen-Induced Nasal Blockage in Experimental Allergic Rhinitis

Journal of Pharmacological Sciences, 2007
It has been hypothesized that air pollution has played a role in the increase in allergy prevalence. However, it remains unclear what exact roles are played by polycyclic aromatic hydrocarbons (PAHs), which are encountered in the environment in the form ...
Nobuaki Mizutani, Takeshi Nabe, Yasuyoshi Ohtani, Hai Yan Han, Masanori Fujii, Shin Yoshino, Teruhisa Hirayama, Shigekatsu Kohno   +7 more
doaj   +1 more source

Three T‐cell determinants of Cry j 1 and Cry j 2, the major Japanese cedar pollen antigens, retain their immunogenicity and tolerogenicity in a linked peptide

Immunology, 2002
SummaryIt has been demonstrated in detail that administration of a dominant T‐cell determinant to animals induces activation or immunological tolerance of T cells. However, it has not been determined whether multiple T‐cell determinants, when integrated into a single peptide, retain their potential to induce T‐cell activation and tolerance. We prepared
Tomomi, Yoshitomi, Kazuki, Hirahara, Junko, Kawaguchi, Nobufusa, Serizawa, Yoshifumi, Taniguchi, Saburo, Saito, Masahiro, Sakaguchi, Sakae, Inouye, Akio, Shiraishi   +8 more
openaire   +3 more sources

Auditory–Tactile Congruence for Synthesis of Adaptive Pain Expressions in RoboPatients

Advanced Robotics Research, EarlyView.
In this work, we explore auditory–tactile congruence for synthesizing adaptive vocal pain expressions in robopatients. Using a robopatient platform that integrates vocal pain sounds with palpation forces, we conducted 7680 trials across 20 participants.
Saitarun Nadipineni, Chapa Sirithunge, Yue Xie, Fumiya Iida, Thilina Dulantha Lalitharatne   +4 more
wiley   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

Determination of Human Linear IgE Epitopes of Japanese Cedar Allergen Cry j 1

Biological and Pharmaceutical Bulletin, 2005
Cry j 1 is one of the major allergens in Japanese cedar pollen. We attempt high throughput analysis and comprehensive identification of the linear IgE epitopes of Cry j 1. A series of overlapping synthetic Cry j 1 peptides chemically spotted on cellulose membrane was probed with sera from patients in Japan and United States, which were reactive to Cry ...
Takagi, Kayoko, Teshima, Reiko, Sawada, Jun-ichi   +2 more
openaire   +3 more sources

Learning Work Function via Implicit Reasoning on Electrostatic Potential Landscapes

Advanced Science, EarlyView.
StructPot‐CLR establishes a cross‐modal contrastive learning framework that aligns the crystal structures of 2D materials with plane‐averaged electrostatic potential landscapes for physically informed work‐function prediction. The model achieves an MAE of 0.265 eV and an R2 of 0.902 on the held‐out test set while accurately preserving key morphological
Haoyu Wan, Yue Wu, Tianhao Su, Deng Pan
wiley   +1 more source

Non-IgE,-IgG4 Antibody to Japanese Cedar Pollen Allergens:Comparison of Its Prevalence and Titers between Pollinosis Patients and Non-Patients

Allergology International, 2005
Background: IgG antibody to allergens in the serum of pollinosis patients is not routinely measured, because there are no simple methods for assaying small amounts of specific IgG in the serum ; so far only IgE and IgG4 antibodies have been assayed.
Hiroshi Miyazawa, Masahiro Sakaguchi, Hiroshi Yasueda, Saburo Saito, Kazuya Tanaka, Kinya Nagata, Sakae Inouye   +6 more
doaj   +1 more source