Results 121 to 130 of about 59,949 (213)

Cryo-EM reveals a right-handed double-helix dimer architecture of PCDH15. [PDF]

open access: yesProc Natl Acad Sci U S A
Liang X   +5 more
europepmc   +1 more source

Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome. [PDF]

open access: yesActa Crystallogr D Struct Biol
Bridges HR   +3 more
europepmc   +1 more source

Discovery of an Antiviral Electron Transfer Process to Create Catalytically Self‐Sufficient Viral Restriction Factors

open access: yesAngewandte Chemie International Edition, EarlyView.
CYB5R3 is identified as a putative electron‐transfer partner of viperin (RSAD2), explaining why ER localisation is required for antiviral activity. Its utilisation enabled the engineering of immune‐silent, catalytically self‐sufficient antiviral restriction factor enzymes (iCAREs) that produce an antiviral nucleoside triphosphate analogue (ANTA ...
Mengdi Wu   +16 more
wiley   +1 more source

A universal Fab targeting a conserved U1A-RNA epitope for RNA structure determination by cryo-EM. [PDF]

open access: yesNucleic Acids Res
Filippova EV   +4 more
europepmc   +1 more source

Structural analysis of Cu/Zn-superoxide dismutase linked to neurodegenerative disease by antibody-guided cryo-EM. [PDF]

open access: yesProtein Sci
Shino Y   +7 more
europepmc   +1 more source

Cryo-EM Structure of the FtsH Periplasmic Domain Reveals Functional Dynamics. [PDF]

open access: yesACS Chem Biol
Göc G   +6 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

open access: yesBMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu   +5 more
wiley   +1 more source

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