Cryo-EM reveals a right-handed double-helix dimer architecture of PCDH15. [PDF]
Liang X +5 more
europepmc +1 more source
Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome. [PDF]
Bridges HR +3 more
europepmc +1 more source
CryoPromptSeg: prompt-guided segmentation with integrated denoising for cryo-EM particle picking. [PDF]
Yang B, You Y, Jin L, Yu H, Zhang L.
europepmc +1 more source
Cryo-EM structure of shutdown human nonmuscle myosin 2A. [PDF]
Casas-Mao D, Carrington G, Peckham M.
europepmc +1 more source
CYB5R3 is identified as a putative electron‐transfer partner of viperin (RSAD2), explaining why ER localisation is required for antiviral activity. Its utilisation enabled the engineering of immune‐silent, catalytically self‐sufficient antiviral restriction factor enzymes (iCAREs) that produce an antiviral nucleoside triphosphate analogue (ANTA ...
Mengdi Wu +16 more
wiley +1 more source
A universal Fab targeting a conserved U1A-RNA epitope for RNA structure determination by cryo-EM. [PDF]
Filippova EV +4 more
europepmc +1 more source
Structural analysis of Cu/Zn-superoxide dismutase linked to neurodegenerative disease by antibody-guided cryo-EM. [PDF]
Shino Y +7 more
europepmc +1 more source
Cryo-EM Structure of the FtsH Periplasmic Domain Reveals Functional Dynamics. [PDF]
Göc G +6 more
europepmc +1 more source
Benchmarking deep learning methods for Cα atom prediction in cryo-EM density maps. [PDF]
Zhang T, Liu Z, Ma Y, Feng C, Han R.
europepmc +1 more source
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source

