Results 101 to 110 of about 6,328,527 (298)
Cryo-EM data collection, model refinement, and validation statistics.
Cryo-EM data collection, model refinement, and validation statistics.
Guibing Liu (16986486) +4 more
core +1 more source
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal +21 more
wiley +1 more source
Background Single-particle cryo-electron microscopy (cryo-EM) has become a mainstream tool for the structural determination of biological macromolecular complexes.
Yanan Zhu, Qi Ouyang, Youdong Mao
doaj +1 more source
Cryo-EM Statistics for Data Collection and Model Quality.
Cryo-EM Statistics for Data Collection and Model Quality.
Asma Hatoum-Aslan (4451431) +7 more
core +1 more source
Protein‐Nanoarchitectures for Low‐Field Intracellular Electro‐Immunomodulation
DHQ‐SDH‐mediated binding of AuNPs drives the formation of interconnected, chain‐like nanoarchitectures with enhanced electrical conductivity. These conductive assemblies undergo macrophage uptake and enable low‐field electrical stimulation, promoting M1‐to‐M2 phenotypic switching with decreased iNOS and increased CD206 expression. Such protein‐mediated
Viktoriya Pakharenko +7 more
wiley +1 more source
Structural rearrangements of the histone octamer translocate DNA
Nucleosomes are dynamic and can move along DNA in an uncatalyzed manner but little is known about the mechanisms of histone octamer translocation. Here the authors present cryo-EM structures of nucleosomes in differently organized histone octamer and DNA
Silvija Bilokapic +2 more
doaj +1 more source
Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng +20 more
wiley +1 more source
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Cryo-EM reconstruction of the DNA-bound PolD binary complex.
(A) Backbone trace of the cryo-EM model of PolD. The blue region was built by fitting the DP1 H451A (PDB ID: 6HMF, this study) and DP2 (PDB ID: 5IJL [15]) crystal structures in the cryo-EM map.
Gérard Pehau-Arnaudet (5657791) +9 more
core +1 more source
Cryo-EM processing of the mACE2/BA.2.12.1 complex.
Cryo-EM processing of the mACE2/BA.2.12.1 complex.
Bertrand Beckert (7941551) +9 more
core +1 more source

