Results 101 to 110 of about 6,328,527 (298)

Cryo-EM data collection, model refinement, and validation statistics.

open access: yes, 2023
Cryo-EM data collection, model refinement, and validation statistics.
Guibing Liu (16986486)   +4 more
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

open access: yesAdvanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal   +21 more
wiley   +1 more source

A deep convolutional neural network approach to single-particle recognition in cryo-electron microscopy

open access: yesBMC Bioinformatics, 2017
Background Single-particle cryo-electron microscopy (cryo-EM) has become a mainstream tool for the structural determination of biological macromolecular complexes.
Yanan Zhu, Qi Ouyang, Youdong Mao
doaj   +1 more source

Cryo-EM Statistics for Data Collection and Model Quality.

open access: yes, 2023
Cryo-EM Statistics for Data Collection and Model Quality.
Asma Hatoum-Aslan (4451431)   +7 more
core   +1 more source

Protein‐Nanoarchitectures for Low‐Field Intracellular Electro‐Immunomodulation

open access: yesAdvanced Functional Materials, EarlyView.
DHQ‐SDH‐mediated binding of AuNPs drives the formation of interconnected, chain‐like nanoarchitectures with enhanced electrical conductivity. These conductive assemblies undergo macrophage uptake and enable low‐field electrical stimulation, promoting M1‐to‐M2 phenotypic switching with decreased iNOS and increased CD206 expression. Such protein‐mediated
Viktoriya Pakharenko   +7 more
wiley   +1 more source

Structural rearrangements of the histone octamer translocate DNA

open access: yesNature Communications, 2018
Nucleosomes are dynamic and can move along DNA in an uncatalyzed manner but little is known about the mechanisms of histone octamer translocation. Here the authors present cryo-EM structures of nucleosomes in differently organized histone octamer and DNA
Silvija Bilokapic   +2 more
doaj   +1 more source

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

open access: yesAdvanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng   +20 more
wiley   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Cryo-EM reconstruction of the DNA-bound PolD binary complex.

open access: yes, 2019
(A) Backbone trace of the cryo-EM model of PolD. The blue region was built by fitting the DP1 H451A (PDB ID: 6HMF, this study) and DP2 (PDB ID: 5IJL [15]) crystal structures in the cryo-EM map.
Gérard Pehau-Arnaudet (5657791)   +9 more
core   +1 more source

Cryo-EM processing of the mACE2/BA.2.12.1 complex.

open access: yes, 2023
Cryo-EM processing of the mACE2/BA.2.12.1 complex.
Bertrand Beckert (7941551)   +9 more
core   +1 more source

Home - About - Disclaimer - Privacy