Results 11 to 20 of about 3,901 (208)

Lessons From Drug Discovery for Cryoprotective Agent Design: An AI-Oriented Perspective. [PDF]

Adv Sci (Weinh)
Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Wilczok D, Valdés-Hernández J, Bernales V, Aspuru-Guzik A, Zhavoronkov A.   +4 more
europepmc   +2 more sources

Predictive Modeling of Bacterial Inactivation With Hydrogen Peroxide Over a Cobalt Ferrite Catalyst. [PDF]

Chemphyschem
Hydrogen peroxide decomposition over a cobalt ferrite catalyst generates hydroxyl radicals for bacterial inactivation. A hybrid machine learning model combining gradient boosting and random forest accurately predicts nonlinear disinfection kinetics, offering a new data‐driven framework for catalytic advanced oxidation processes and intelligent water ...
Husak V, Danyliuk N, Roubik H, Bobrova O, Hammond SDH, Shyichuk A.   +5 more
europepmc   +2 more sources

Cryobiology [Kriobiyoloji]

, 2000
By the advances and understandings in physics and mammalian cell biology, cryobiology makes us able to store our valuable biological materials and use them when wanted. The spectrum of materials is wide-spread from haploid gamete cells to cells processed via genetic engineering.
Aktan, Tahsin Murad, Çıray, N., Tosun, M., Duman, S., Erdoğan, E.   +4 more
openaire   +2 more sources

Biobanked Liver Organoids: A Roadmap for Precision Hepatology. [PDF]

Bioessays
Cryopreservation‐enabled biobanking transforms archived human liver tissue into standardized, quality‐controlled organoid resources. By decoupling organoid generation from the availability of fresh tissue, this infrastructure enables scalable, reproducible, and clinically actionable liver models that support precision hepatology, drug development, and ...
Cabré EJ, Cobo-González S, Valle LS, Martínez S, Ramos-Álvarez MDP, Sáez-Álvarez Y.   +5 more
europepmc   +2 more sources

Red LED Treatment Confers Superior Early Post-Thaw Sperm Kinetic Resilience and Identifies Progressive Motility as the Most Informative Functional Marker in Dogs. [PDF]

Reprod Domest Anim
ABSTRACT LED‐based photobiomodulation has attracted increasing interest as a potential strategy to improve post‐thaw sperm performance, but its biological relevance in canine semen remains poorly defined. This study investigated whether blue and red LED exposure influences baseline sperm quality and the dynamic pattern of post‐thaw sperm deterioration ...
de Oliveira RS, de Lara NSS, Silvestri M, de Souza SF, Kozicki LE, Demeterco D, Vaz ES, de Oliveira FSR, Moure VR, Valdameri G, Souza FA.   +10 more
europepmc   +2 more sources

Hydrohalite spatial distribution in frozen cell cultures measured using confocal Raman microscopy

, 2022
S.41-47Hydrohalite, a crystalline rock salt hydrate, (NaCl·2H2O), can form in cryopreservation samples under certain circumstances changing the local chemical environment of the preserved cells.
Stracke, F., Kreiner-Møller, A., Zimmermann, H.   +2 more
core   +1 more source

Changes in the sensitivity of mammalian erythrocytes to hypertonic shock and cryohemolysis under the pretreatment by phenylhydrazine

Вісник Харківського Національного Університету Імені В.Н. Каразіна: Серія Біологія, 2023
The effect of pretreating mammalian erythrocytes with phenylhydrazine on their sensitivity to hypertonic shock and hypertonic cryohemolysis was investigated.
O. Nipot, N. Yershova, S. Yershov, O. Chabanenko, N. Shpakova   +4 more
doaj   +1 more source

A comparative evaluation of semen parameters in pre- and post-Hurricane Katrina human population

Asian Journal of Andrology, 2015
A natural disaster leading to accumulation of environmental contaminants may have substantial effects on the male reproductive system. Our aim was to compare and assess semen parameters in a normospermic population residing in the Southern Louisiana, USA
Caner Baran, Wayne J Hellstrom, Suresh C Sikka   +2 more
doaj   +1 more source

The role of the dehydration stage in the post-hypertonic hemolysis of mammalian erythrocytes

Біологія тварин, 2021
The aim of this study was to assess the level of damage to mammalian erythrocytes under post-hypertonic shock depending on the concentration of NaCl in the dehydration medium and to determine the effect of hypertonic NaCl solutions on the condition of ...
O. E. Nipot, O. O. Shapkina, P. M. Zubov, N. V. Orlova, N. M. Shpakova   +4 more
doaj   +1 more source

Three-dimensional printing with polylactic acid (PLA) thermoplastic offers new opportunities for cryobiology [PDF]

, 2016
Development of devices through design, prototyping, testing, and fabrication is especially necessary for enhancement of research and eventual application in cryobiology.
Tiersch, Terrence R., Monroe, William T.
core   +1 more source