Results 21 to 30 of about 6,755 (169)

Interaction of polymorphism of the interleukin-6 gene with immunological damages and their role in the development of mixed cryoglobulinemia in patients with chronic hepatitis C

open access: yesPatologìâ, 2019
Aim. To determine the role of the relationship of immunological disorders with interleukin-6 gene polymorphism in the formation of HCV-associated mixed cryoglobulinemia. Materials and methods.
K. V. Kalashnyk   +2 more
doaj   +1 more source

IgG cryoglobulinemia.

open access: yesEuropean review for medical and pharmacological sciences, 2018
Mixed Cryoglobulinemia is the most well-known Hepatitis C Virus (HCV)-associated extrahepatic manifestation. MC is both an autoimmune and B-lymphoproliferative disorder. Cryoglobulins (CGs) are classified into three groups according to immunoglobulin (Ig) composition: type I is composed of one isotype or Ig class.
Gulli, F   +9 more
openaire   +4 more sources

Concomitant Nephrotic Syndrome and Cryoglobulinemia in a Case of Malignant Mesothelioma

open access: yesCase Reports in Nephrology, 2022
Malignant pleural mesothelioma is rarely associated with nephrotic syndrome. Cryoglobulinemia is found in various pathological statuses, such as hepatitis C virus infection but rarely in malignant neoplasms.
Kei Nagai   +3 more
doaj   +1 more source

Cryoglobulinemia (Review)

open access: yesMolecular Medicine Reports, 2012
Cryoglobulins are immunoglobulins that precipitate at low temperatures and redissolve upon rewarming. Cryoglobulinemia refers to the presence of circulating cryoglobulins in serum, and generally leads to a systemic inflammatory syndrome characterized by fatigue, arthralgia, purpura, neuropathy and glomerulonephritis.
Shimon, Takada   +7 more
openaire   +3 more sources

Clinical Diversity and Treatment Outcomes in IgM Monoclonal Gammopathy Associated with Cold Agglutinin Disease and Cryoglobulinemia: A Single Center Study [PDF]

open access: yesDocumenta Haematologica
Background: Cold agglutinin disease (CAD) and cryoglobulinemia are rare immune-mediated complications of IgM monoclonal gammopathies, such as Waldenström macroglobulinemia (WM) and monoclonal gammopathy of undetermined significance (MGUS).
Larisa ZIDARU   +5 more
doaj   +1 more source

Cryoglobulinemia in systemic lupus erythematosus: a retrospective study of 213 patients

open access: yesArthritis Research & Therapy, 2022
Highlights • Cryoglobulinemia is frequent in SLE, but mostly asymptomatic. • Sixty-six percent of SLE patients tested positive for cryoglobulins, and 15% of the SLE patients with cryoglobulinemia developed a cryoglobulinemic vasculitis. • Features of the
Yoann Roubertou   +11 more
doaj   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori   +5 more
wiley   +1 more source

Mixed cryoglobulinemia [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2008
Mixed cryoglobulinemia (MC), type II and type III, refers to the presence of circulating cryoprecipitable immune complexes in the serum and manifests clinically by a classical triad of purpura, weakness and arthralgias. It is considered to be a rare disorder, but its true prevalence remains unknown. The disease is more common in Southern Europe than in
openaire   +4 more sources

Peripheral Ulcerative Keratitis and Necrotizing Scleritis Initiated by Trauma in the Setting of Mixed Cryoglobulinemia

open access: yesCase Reports in Ophthalmology, 2011
Purpose: To report a case of peripheral ulcerative keratitis and necrotizing scleritis precipitated by trauma in a patient with mixed cryoglobulinemia due to hepatitis C viral infection. Methods: Case report and literature review.
Cameron Campbell Johnson   +1 more
doaj   +1 more source

A Devastating Case of Hepatitis C-Induced Mixed Cryoglobulinemia

open access: yesCase Reports in Hepatology, 2021
Hepatitis C-induced mixed cryoglobulinemia leading to rapidly progressive gangrene, necessitating amputations, is a rare presentation. We describe a case of a 55-year-old man with untreated chronic hepatitis C virus (HCV) presenting with arthralgia and ...
Sameeha Khalid   +5 more
doaj   +1 more source

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