Results 31 to 40 of about 6,755 (169)

Smooth muscle antibodies and cryoglobulinemia are associated with advanced liver fibrosis in Brazilian hepatitis C virus carriers

open access: yesBrazilian Journal of Infectious Diseases
Cryoglobulinemia and non-organ-specific-autoantibody are biomarkers of autoimmunity of the chronic infection caused by hepatitis C virus (HCV).
Luis Jesuino de Oliveira Andrade   +7 more
doaj   +1 more source

Cryoglobulinemia due to Hepatitis C with Pulmonary Renal Syndrome

open access: yesCase Reports in Nephrology, 2013
Cryoglobulinemia is an uncommon condition typically due to hepatitis C infection. Its clinical presentation is varied and often reflects deposition of immune complex and complement deposition.
Tariq Abdulkarim   +2 more
doaj   +1 more source

Clinical Characteristics of Cryoglobulinemia With Cardiac Involvement in a Single Center

open access: yesFrontiers in Cardiovascular Medicine, 2022
Background: Cryoglobulinemia is a syndrome characterized by the presence of cryoglobulins (CGs) in serum, and cardiac involvement is a rare occurrence that can affect treatment and prognosis.
Kun He   +5 more
doaj   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, Volume 78, Issue 7, Page 860-874, July 2026.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

Successful Daratumumab, Lenalidomide, and Dexamethasone Treatment of Refractory Type I Cryoglobulinemia From Monoclonal Gammopathy of Undetermined Significance

open access: yesAnnals of Internal Medicine: Clinical Cases
Cryoglobulinemia is a rare inflammatory condition, with 3 major types, and has infectious, autoimmune, or malignant etiologies. Cryoglobulinemia can lead to systemic vasculitis that will require identification of the underlying cause to tailor treatment.
Karen J. Shou, Karen G. Zeman
doaj   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

open access: yesArthritis &Rheumatology, Volume 78, Issue 7, Page 1393-1402, July 2026.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Prevalence of cryoglobulinemia and cryoglobulinemic vasculitis in chronically HCV-infected Brazilian patients

open access: yesAnnals of Hepatology, 2019
Introduction and Objectives: Cryoglobulinemia is one of the most frequent extrahepatic manifestations of chronic hepatitis C virus (HCV) infection and it may evolve to cryoglobulinemic vasculitis (CryoVas) which is a systemic vasculitis that affects ...
Mariana Freitas-de Aguiar   +6 more
doaj   +1 more source

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer

open access: yesImmunology, Volume 178, Issue 3, Page 377-386, July 2026.
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros   +5 more
wiley   +1 more source

Cryoglobulinemia in a child

open access: yesIndian Journal of Dermatology, 2010
Cryoglobulinemia is a rare condition. We report a case of cryoglobulinemia in 1.5-year-old boy, who presented with bluish black discoloration of hands and feet. Serum was positive for cryoglobulins. The serum cryoglobulin level was 70 μg/ml (normal
openaire   +3 more sources

Enhanced activation of memory, but not naïve, B cells in chronic hepatitis C virus-infected patients with cryoglobulinemia and advanced liver fibrosis. [PDF]

open access: yesPLoS ONE, 2013
Mixed cryoglobulinemia is the most common extrahepatic disease manifestation of chronic hepatitis C virus (HCV) infection, where immunoglobulins precipitate at low temperatures and cause symptoms such as vasculitis, glomerulonephritis and arthralgia. HCV-
Deanna M Santer   +5 more
doaj   +1 more source

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