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Cryoglobulinemia Vasculitis [PDF]
Cryoglobulinemic vasculitis (CryoVas) is a small-vessel vasculitis involving mainly the skin, the joints, the peripheral nervous system, and the kidneys. Type I CryoVas is single monoclonal immunoglobulins related to an underlying B-cell lymphoproliferative disorder. Type II and III cryoglobulins, often referred to as mixed cryoglobulinemia, consist of
Cacoub, Patrice +4 more
openaire +5 more sources
Secular trends in cryoglobulinemia mortality in the USA in the era of direct-acting antivirals
Background Hepatitis C virus (HCV) is the main etiology of cryoglobulinemia with mortality around 25%. Little is known on the changes in cryoglobulinemia mortality after the introduction of direct-acting antivirals (DAA) for treatment of HCV in 2014 in ...
Qianyu Guo +5 more
doaj +1 more source
BackgroundHow cryoglobulinemia evolves after sustained virological response (SVR) following direct-acting antiviral (DAA) treatment in Asian hepatitis C virus (HCV)-infected patients remains elusive.MethodsA prospective cohort study was conducted in 422 ...
Ming-Ling Chang +13 more
doaj +1 more source
Abstract Mixed cryoglobulinemia (MC) type II is a disorder characterized by circulating cold-precipitable immune complexes composed of polyclonal immunoglobulin IgG and monoclonal IgM rheumatoid factor (RF). The systemic vasculitis which characterizes the disease is caused by the deposition of immune complexes on the walls of small ...
M, Oliver +5 more
openaire +5 more sources
Sequential central retinal artery occlusions associated with cryoglobulinemia
Background Cryoglobulinemia, the presence of serum cryoglobulins which are immunoglobulins or complement components that precipitate at temperatures below 37 °C, commonly present with cutaneous manifestations initially, but are more rarely associated ...
Patrick Wang +3 more
doaj +1 more source
Mixed cryoglobulinemia refers to the serum presence of a variety of cryoglobulins, which are defined as immunoglobulins that precipitate at temperatures of < 37°C. The most common cause of mixed cryoglobulinemia is hepatitis C virus (HCV), while other
Jiao Luo +7 more
doaj +1 more source
Cryoglobulinemia and non-organ-specific-autoantibody are biomarkers of autoimmunity of the chronic infection caused by hepatitis C virus (HCV).
Luis Jesuino de Oliveira Andrade, PhD +7 more
doaj +1 more source
Leukocytoclastic Vasculitis in a Patient with Type 1 Cryoglobulinemia
Cutaneous manifestations of type 1 cryoglobulinemia are usually related to vascular occlusion by noninflammatory thrombosis; rarely is leukocytoclastic vasculitis seen in type 1 cryoglobulinemia.
Paul Y. Liu, Pamela E. Prete, Gary Kukes
doaj +1 more source
Objective – to discover role of immune disorders in clinical manifestations formation of mixed cryoglobulinemia in patients with CHC. Material and methods. 214 patients with CHC were included in the study.
O. O. Furyk +2 more
doaj +1 more source
Hepatitis C virus (HCV) infects B-lymphocytes, provokes cellular dysfunction and causes lymphoproliferative diseases such as cryoglobulinemia and non-Hodgkin's B-cell lymphoma.
Isabela S. Oliveira +5 more
doaj +1 more source

