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Cryoglobulinemia is a rare inflammatory condition, with 3 major types, and has infectious, autoimmune, or malignant etiologies. Cryoglobulinemia can lead to systemic vasculitis that will require identification of the underlying cause to tailor treatment.
Karen J. Shou, Karen G. Zeman
doaj +1 more source
Audio-vestibular symptoms in systemic autoimmune diseases [PDF]
Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce +7 more
core +1 more source
Introduction and Objectives: Cryoglobulinemia is one of the most frequent extrahepatic manifestations of chronic hepatitis C virus (HCV) infection and it may evolve to cryoglobulinemic vasculitis (CryoVas) which is a systemic vasculitis that affects ...
Mariana Freitas-de Aguiar +6 more
doaj +1 more source
Hepatitis C virus and non-Hodgkin's lymphomas: Meta-analysis of epidemiology data and therapy options. [PDF]
Hepatitis C virus (HCV) is a global health problem affecting a large fraction of the world\u2019s population: This virus is able to determine both hepatic and extrahepatic diseases.
Bulian, P +8 more
core +1 more source
A Framework for Emergency Department–Integrated Hepatitis C Test‐and‐Treat in the United States
ABSTRACT Despite the availability of curative, direct‐acting antiviral therapy, hepatitis C virus elimination remains incomplete. Losses across the care cascade continue to limit impact, from initial diagnosis to sustained virologic response. Fewer than 1/3 of individuals ultimately achieve cure. These gaps reflect a delivery system that does not align
Saeed S. Graham
wiley +1 more source
Immunological alterations in hepatitis C virus infection [PDF]
A higher prevalence of immunological processes has recently been reported in patients with hepatitis C virus (HCV) infection, focusing the attention of physicians and researchers on the close association between HCV and immune disorders.
Calvaruso, V., Craxi, A.
core +1 more source
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley +1 more source
Enhanced activation of memory, but not naïve, B cells in chronic hepatitis C virus-infected patients with cryoglobulinemia and advanced liver fibrosis. [PDF]
Mixed cryoglobulinemia is the most common extrahepatic disease manifestation of chronic hepatitis C virus (HCV) infection, where immunoglobulins precipitate at low temperatures and cause symptoms such as vasculitis, glomerulonephritis and arthralgia. HCV-
Deanna M Santer +5 more
doaj +1 more source
ABSTRACT Immunocompromised individuals experience an impaired immune function due to conditions that might be either congenital or acquired over the course of their lives. Epidemiological studies often rely on clinical definitions which, in some cases, benefit from being translated into machine‐readable algorithms for application to electronic health ...
Judit Riera‐Arnau +62 more
wiley +1 more source
Pulmonary Hemorrhage in Cryoglobulinemia
Pulmonary manifestations of cryoglobulinemia are uncommon and their clinical behaviour is unpredictable, ranging from mild dyspnea to life-threatening presentations.
G Kirkpatrick +3 more
doaj +1 more source

