Results 61 to 70 of about 12,154 (216)

The Complement System in ANCA‐Associated Vasculitis: Mechanistic Insights, Therapeutic Horizons, and Unmet Clinical Needs

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
Complement activation, particularly via the alternative pathway, drives inflammation and organ damage in ANCA‐associated vasculitis. This review highlights mechanistic insights, tissue and biomarker evidence, and clinical implications of targeting the C5a–C5aR1 axis.
Kehinde Sunmboye, Pauline Millan
wiley   +1 more source

Risk factors for relapse in non-infectious cryoglobulinemic vasculitis, including type I cryoglobulinemia: a systematic review

open access: yesFrontiers in Immunology, 2023
BackgroundData on non-infectious cryoglobulinemic vasculitis (NICV) is scarce, especially concerning the management of relapses, which are troublesome.
Nithya Rajendran   +2 more
doaj   +1 more source

Hepatitis C virus syndrome: A constellation of organ- and non-organ specific autoimmune disorders, B-cell non-Hodgkin's lymphoma, and cancer [PDF]

open access: yes, 2015
The clinical course of chronic hepatitis C virus (HCV) infection is characterized by possible development of both liver and extrahepatic disorders. The tropism of HCV for the lymphoid tissue is responsible for several immune-mediated disorders; a poly ...
Antonelli, Alessandro   +7 more
core   +1 more source

Steroid‐Refractory Cryptogenic Organising Pneumonia (COP) in a Patient With Mannose‐Binding Lectin (MBL) Deficiency

open access: yesRespirology Case Reports, Volume 14, Issue 2, February 2026.
A 67‐year‐old man with cryptogenic organising pneumonia developed recurrent relapses despite corticosteroid and mycophenolate therapy. A complete absence of mannose‐binding lectin was identified, suggesting impaired apoptotic cell clearance as a contributor to persistent inflammation.
Ilias E. Dimeas   +4 more
wiley   +1 more source

Non-infectious mixed cryoglobulinemia as a new clinical presentation of mutation in the gene encoding coatomer subunit alpha: a case report of two adult sisters

open access: yesFrontiers in Immunology
Cryoglobulinemia is a rare disease characterized by the presence of cryoglobulins in the blood serum. It is usually caused by autoimmune, lymphoproliferative, or infectious factors.
Ksymena Leśniak   +6 more
doaj   +1 more source

Cryoglobulinemic vasculitis and glomerulonephritis: concerns in clinical practice

open access: yesChinese Medical Journal, 2019
. Objective:. Cryoglobulinemia often causes systemic vasculitis, thereby damaging to skin and internal organs including kidneys, even life-threatening. This review aimed to introduce the advances in understanding, detection, and treatment of this disease
Yi-Pu Chen   +4 more
doaj   +1 more source

Treatment of chronic hepatitis C-associated cryoglobulinemia vasculitis at the era of direct-acting antivirals

open access: yesTherapeutic Advances in Gastroenterology, 2020
Hepatitis C virus (HCV) infection is responsible for both hepatic and extrahepatic manifestations. Before the era of direct-acting antivirals (DAA), cryoglobulinemia was related to HCV infection in 70–90% of cases. Observed in 30% to 40% of patients with
Cloé Comarmond   +2 more
doaj   +1 more source

A Case of IgG4‐Related Disease That Mimics an Anterior Mediastinal Malignant Tumour

open access: yesRespirology Case Reports, Volume 14, Issue 1, January 2026.
We describe a rare case of IgG4‐related disease presenting as an anterior mediastinal mass mimicking malignancy. This case demonstrates the importance of considering IgG4‐related disease in the differential diagnosis of mediastinal tumours, even when FDG‐PET shows abnormal accumulation and serum IgG4 levels are not particularly high.
Noriaki Nishimura   +12 more
wiley   +1 more source

Mixed Cryoglobulinemia in a Patient with Juvenile Idiopathic Arthritis

open access: yesCase Reports in Rheumatology, 2019
Cryoglobulinemia is a rare illness of cryoglobulin accumulation in the blood which can typically present with arthralgia, purpura, skin ulcers, glomerulonephritis, and peripheral neuropathy.
Fahad Bnatig   +3 more
doaj   +1 more source

Successful renal transplantation to a recipient with type II cryoglobulinemia: a case report

open access: yesBMC Nephrology, 2018
Background Recurrence of glomerulonephritis is an important risk factor for renal graft dysfunction. Cryoglobulinemia is known as a relatively rare cause of renal failure, and doctors are usually hesitant to perform transplantation on a recipient with ...
Tomomichi Kasagi   +4 more
doaj   +1 more source

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