Results 121 to 130 of about 68,611 (312)

S100A9 promotes pulmonary arterial hypertension by regulating mitochondria–endoplasmic reticulum interaction‐mediated inflammatory injury of endothelial cells

Interdisciplinary Medicine, EarlyView.
Macrophage‐derived S100 calcium‐binding protein A9 (S100A9) promotes the pathological progression of pulmonary arterial hypertension (PAH). S100A9 upregulates the interaction between signal‐transducing adaptor protein 2 and leucine‐rich repeat kinase 2, thereby regulating mitochondria–endoplasmic reticulum (ER) contact.
Chen Gong, Long Chen, Yiting Zhao, Xiaohe Wang, Qiang Yuan, Xiaofeng Fang, Liuyi Li, Yinbo Xu, Shumei Jiang, Guangwen Xu, Ke Meng, Delong Wang, Kangli Cao, Jianlong Sheng, Liling Guo, Shichun Shen   +15 more
wiley   +1 more source

Cryopreservation of tropical plant germplasm. Current research progress and application

, 2000
This publication includes the papers presented during an international workshop held in Tsukuba, Japan in October, 1998 which was jointly organized by JIRCAS and IPGRI.
Engelmann, Florent (ed.), Takagi, Hiroko (ed.)   +1 more
core  

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

The Oocyte/Antral Follicle Count Index: Does Maximizing Oocyte Yield Translate into Better Assisted Reproductive Technology Outcomes?

Journal of Ultrasound in Medicine, EarlyView.
Objectives Whether aspiration of more oocytes than the antral follicle count (AFC) is beneficial for the current and future products of assisted reproductive technologies (ART) cycles. Methods Data of the first oocyte aspiration for intracytoplasmic sperm injection performed between 2018 and 2022 in attempt to conceive (ICSI, n = 399) or for planned ...
Shir Danieli‐Gruber, Onit Sapir, Dan Netanely, Avital Wertheimer, Avi Ben‐Haroush, Eran Altman, Tzippy Shochat, Yoel Shufaro   +7 more
wiley   +1 more source

A review on the functional roles of trehalose during cryopreservation of small ruminant semen

Frontiers in Veterinary Science
Sperm cryopreservation is an approach to preserve sperm cells in liquid nitrogen or other cryogenic media for future use in assisted reproductive technologies, such as in vitro fertilization or artificial insemination.
Baoyu Jia, Larbi Allai, Larbi Allai, Larbi Allai, Chunyan Li, Chunyan Li, Chunyan Li, Jiachong Liang, Jiachong Liang, Jiachong Liang, Chunrong Lv, Chunrong Lv, Chunrong Lv, Guoquan Wu, Guoquan Wu, Guoquan Wu, Guobo Quan, Guobo Quan, Guobo Quan   +18 more
doaj   +1 more source

Development of Islet Cryopreservation for Type 1 Diabetes Cell Therapy

Zhileng xuebao, 2021
In recent years, cell therapy technology for type 1 diabetes has advanced rapidly, but the lack of donor pancreatic islets and the time and space mismatch between donor and recipient limits its clinical application. Cryopreservation technology provides a
Han Hengxin, Zhan Taijie, Cui Mengdong, Yang Jiamin, Chen Liang, Xu Yi   +5 more
doaj  

Oocytes cryopreservation: in which circumstances? Who should pay? Approaches amongst attending IVF physicians and researchers in the field of bioethics and health regulation

, 2010
In recent years there have been significant advances in the process of oocyte cryopreservation. Advanced techniques including vitrification have seen increasing success rates of fertilization.
Malkiel, Avishay, Lehmann, Lisa Soleymani, Brezis, Mayer, Chinitz, David   +3 more
core  

Associations of Monocyte Glucocerebrosidase with Cognition and Cholinergic Innervation in GBA1 Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background The GBA1 gene encodes the lysosomal enzyme glucocerebrosidase (GCase). Parkinson's disease (PD) patients carrying a GBA1 variant (GBA‐PD) exhibit faster cognitive decline, linked to cholinergic degeneration. Objectives The aim was to investigate whether GCase activity, measured in monocytes, correlates with cognitive dysfunction or ...
Sofie Slingerland, Sygrid van der Zee, Sven C.D. van Ijzendoorn, Anne C. Slomp, Jeffrey M. Boertien, Sanne K. Meles, Arjan Kol, Marie Geerlings, Teus van Laar   +8 more
wiley   +1 more source

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

Pediatric Discovery, EarlyView.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang, Xiao Yuan, Yi Yang, Philip N. Baker, Mark D. Kilby, Chao Tong, Xi Yuan   +6 more
wiley   +1 more source

Cryopreservation of Avian Semen

, 2020
Cryopreservation protocols for semen exist for bird species used in animal production, fancy and hobby species, and wild bird species. Freezing of bird oocytes or embryos is not possible. Cryopreservation of avian semen is used for preserving (genetic diversity of) endangered species or breeds.
openaire   +2 more sources