Results 131 to 140 of about 108,976 (266)

Collection and freezing of equine epididymal spermatozoa [PDF]

open access: yes, 2014
The epididymis and vas deferens store an important number of fertile spermatozoa called the extragonadal sperm reserves. These stored spermatozoa can be collected in an ultimate attempt to preserve viable spermatozoa of a critically ill or dying stallion.
Govaere, Jan   +5 more
core   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

open access: yesIbrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Recent advances of the egg\'s freezing: An overview

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
It is now more than three decades since the first live birth from oocyte cryopreservation. At present, oocyte cryopreservation has become a major component of Assisted Reproductive technologies (ART).
Faranak Aghaz, Mozafar Khazaei
doaj  

Efficacy and immunogenic effects of Tumor Treating Fields (TTFields) in preclinical models of pancreatic ductal adenocarcinoma, with and without gemcitabine/nab‐paclitaxel

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Adaptive immune responses are typically limited in pancreatic ductal adenocarcinoma, resulting in minimal efficacy of immune checkpoint inhibitors. Tumor Treating Fields (TTFields) therapy, which uses low‐intensity intermediate‐frequency electric fields to disrupt cancer cell processes, has been approved for certain cancers.
Tal Kan   +21 more
wiley   +1 more source

The Oocyte/Antral Follicle Count Index: Does Maximizing Oocyte Yield Translate into Better Assisted Reproductive Technology Outcomes?

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives Whether aspiration of more oocytes than the antral follicle count (AFC) is beneficial for the current and future products of assisted reproductive technologies (ART) cycles. Methods Data of the first oocyte aspiration for intracytoplasmic sperm injection performed between 2018 and 2022 in attempt to conceive (ICSI, n = 399) or for planned ...
Shir Danieli‐Gruber   +7 more
wiley   +1 more source

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

open access: yesPediatric Discovery, EarlyView.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang   +6 more
wiley   +1 more source

Single‐Cell Nanodroplet Processing Proteomics Pipeline for Analysis of Human‐Derived Microglia

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Single‐cell omics tools provide unique insights into heterogeneous cell populations and their responses to stimuli. For example, single‐cell RNA sequencing has identified several transcriptionally distinct populations of microglia, which are resident immune cells of the central nervous system (CNS) that are responsive to CNS injury, infection,
Ashley N. Ives   +7 more
wiley   +1 more source

Macrophage Phenotype–Dependent Protein Corona Formation Governs Ligand Accessibility and Immune Clearance of Biomimetic Nanoparticles

open access: yesSmall, EarlyView.
Macrophage phenotype dictates protein corona composition and immune clearance of biomimetic nanoparticles. M0‐derived membranes minimize opsonin adsorption and complement activation, enabling superior immune evasion and prolonged circulation, thereby providing mechanistic insights for designing long‐circulating nanocarriers.
Tianchang He   +8 more
wiley   +1 more source

Biopreservation of hepatocytes: current concepts on hypothermic preservation, cryopreservation, and vitrification [PDF]

open access: yes, 2013
Isolated liver cells (primarily isolated hepatocytes) have found important applications in science and medicine over the past 40 years in a wide range of areas, including physiological studies, investigations on liver metabolism, organ preservation and ...
Balaban, Cecilia Lucía   +5 more
core  

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