Results 51 to 60 of about 79,865 (300)

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

open access: yesAdvanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García   +13 more
wiley   +1 more source

Fertility Cryopreservation

open access: yes, 2012
The cryobiology is the science of low temperature biology. Fertility cryopreservation is a vital branch of reproductive science and involves the preservation of gametes (sperm and oocytes), embryos, and reproductive tissues (ovarian and testicular tissues) for use in assisted reproduction techniques (ART).
CIANI, FRANCESCA   +3 more
openaire   +3 more sources

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

Біотехнологічні методи оцінки ефективності кріоконсервації сперми кнурів

open access: yesФактори експериментальної еволюції організмів, 2017
Aim. Estimate boar semen for suitability to cryopreservation using informative biotechnological methods (thermoresistant probe, heat resistance test) to replenish genetic resources of Animal Gene bank Institute of Animal Breeding and Genetics n.
S. I. Kovtun   +4 more
doaj   +1 more source

Restoring Sperm Quality Post-Cryopreservation Using Mitochondrial-Targeted Compounds

open access: yesAntioxidants, 2022
While critical for male fertility preservation, cryopreservation damage reduces sperm quality and fertilization potential. This study investigated whether the addition of mitochondrial-targeted, antioxidant compounds, also known as Mitochondrial ...
Macarena Gonzalez   +5 more
doaj   +1 more source

Cell separation and cryopreservation of cord blood fractions for immunotherapeutic applications [PDF]

open access: yes, 2014
In 2008 Anthony Nolan opened the UK’s first public umbilical cord blood (CB) bank (Anthony Nolan Cell Therapy Centre, ANCTC) in which CB is stored for haematopoietic stem cell (HSC) transplantation. Due to strict quality thresholds, the majority of units
Fry, LJ
core  

Cryopreservation of animal oocytes and embryos: current progress and future prospects [PDF]

open access: yes, 2016
Cryopreservation describes techniques that permit freezing and subsequent warming of biological samples without loss of viability. The application of cryopreservation in assisted reproductive technology encompasses the freezing of gametes, embryos and ...
Fowler, K.   +7 more
core   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang   +3 more
wiley   +1 more source

Apoptotic Cell Death and Function of Cryopreserved Porcine Hepatocytes in a Bioartificial Liver

open access: yesCell Transplantation, 2003
We have previously shown that cryopreservation leads to increased apoptotic death of porcine hepatocytes intended for use in a bioartificial liver (BAL).
Takakazu Matsushita   +7 more
doaj   +1 more source

Cryopreservation by Directional Freezing and Vitrification Focusing on Large Tissues and Organs

open access: yesCells, 2022
The cryopreservation of cells has been in routine use for decades. However, despite the extensive research in the field, cryopreservation of large tissues and organs is still experimental.
Amir Arav
doaj   +1 more source

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