Results 61 to 70 of about 33,639 (248)

Apoptotic Cell Death and Function of Cryopreserved Porcine Hepatocytes in a Bioartificial Liver

Cell Transplantation, 2003
We have previously shown that cryopreservation leads to increased apoptotic death of porcine hepatocytes intended for use in a bioartificial liver (BAL).
Takakazu Matsushita, Toshikazu Yagi, Joseph A. Hardin, Jennifer D. Cragun, Frank W. Crow, H. Robert Bergen, Gregory J. Gores, Scott L. Nyberg M.D., Ph.D.   +7 more
doaj   +1 more source

Біотехнологічні методи оцінки ефективності кріоконсервації сперми кнурів

Фактори експериментальної еволюції організмів, 2017
Aim. Estimate boar semen for suitability to cryopreservation using informative biotechnological methods (thermoresistant probe, heat resistance test) to replenish genetic resources of Animal Gene bank Institute of Animal Breeding and Genetics n.
S. I. Kovtun, O. I. Metlytska, O. V. Shcherbak, V. M. Hyria, K. V. Kopylova   +4 more
doaj   +1 more source

Cell separation and cryopreservation of cord blood fractions for immunotherapeutic applications [PDF]

, 2014
In 2008 Anthony Nolan opened the UK’s first public umbilical cord blood (CB) bank (Anthony Nolan Cell Therapy Centre, ANCTC) in which CB is stored for haematopoietic stem cell (HSC) transplantation. Due to strict quality thresholds, the majority of units
Fry, LJ
core  

Overall approach to fertility preservation and ındications for ovarian tissue harvesting and cryopreservation

, 2022
The field of fertility preservation has significantly evolved in the last two decades. Embryo, oocyte, and ovarian tissue cryopreservation are the well-established options for women pursuing fertility preservation.
Öktem, Özgür, Türkgeldi, Engin, Turan, Volkan   +2 more
core   +1 more source

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

Advanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, Chunfang Zhang, Guangtong Deng   +11 more
wiley   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Coconut Cryopreservation: Present Status and Future Prospects

CORD, 2017
Coconut is one of the most important small holder crops worldwide. Conservation of coconut as seeds or field gene banks is not effective due to a range of limitations.
Iroshini Welewanni, Dharshani Bandupriya
doaj   +1 more source

Cryopreservation [PDF]

Organogenesis, 2009
In 1949 Polge, Parks and Smith1 reported on the “chance” discovery of glycerol's cryoprotective function during their efforts to preserve avian spermatozoa in the frozen state.
John G, Baust, Dayong, Gao, John M, Baust   +2 more
openaire   +2 more sources

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

INNOVATIVE BIOMATERIALS FOR DEVELOPMENT OF NEW STRATEGIES TO PRESERVE FERTILITY IN CANCER WOMEN [PDF]

, 2011
Currently, embryo and oocyte cryopreservation are the most used strategies to preserve fertility in cancer women. However, for prepuberal patients or patients who have an estrogen sensitive cancer, they are not an option.
Barbato, Vincenza
core   +1 more source