Results 81 to 90 of about 33,639 (248)

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

The generation of live offspring from vitrified oocytes [PDF]

, 2011
Oocyte cryopreservation is extremely beneficial for assisted reproductive technologies, the treatment of infertility and biotechnology and offers a viable alternative to embryo freezing and ovarian grafting approaches for the generation of embryonic stem
Sanchez-Partida, Luis, Sumer, Huseyin, Sumer, H, Kelly, Richard, Lo, Camden, Kelly, RDW, Aharon, R, Moira K. O'Bryan, Kelly Richard D. W., Michael K. Holland, Camden Y. Lo, O'Bryan Moira K., St. John, Justin C., Justin C St John, Camden Y Lo, St John, Justin C., L. Gabriel Sanchez-Partida, Sumner, Huseyin, Sanchez-Partida L. Gabriel, John St., JC, St John, Justin, Sanchez-Partida, L. Gabriel, Richard D W Kelly, Michael K Holland, Moira K O'Bryan, St. John Justin C., Aharon Rotem, Sumer Huseyin, Lo Camden Y., Holland, Michael K., O'Bryan, Moira K., Rotem Aharon, Aharon, Rotem, Justin C. St. John, Holland Michael K., Sanchez-Partida, LG, O'Bryan, Moira, Lo, CY, Holland, MK, Lo, Camden Y., Huseyin Sumer, L Gabriel Sanchez-Partida, Richard D. W. Kelly, Kelly, Richard D. W., Sanchez-Partilda, L. Gabriel, O'Bryan, MK, Holland, Michael   +46 more
core   +2 more sources

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

Pathways to motherhood: A single-center retrospective study on fertility preservation and reproductive outcomes in patients with breast cancer

Journal of the Formosan Medical Association
Background: Breast cancer treatments often have negative effects on fertility, which pose challenges among patients who want to be parents in the future.
Chao-Ying Chen, Yu-Chiao Yi, Hwa-Fen Guu, Ya-Fang Chen, Hsiao-Fan Kung, Jui-Chun Chang, Li-Yu Chen, Chih-Chiang Hung, Ming-Jer Chen   +8 more
doaj   +1 more source

CRYOPRESERVATION OF REPRODUCTIVE PRODUCTS AS AN EFFECTIVE METHOD FOR PRESERVING THE BIODIVERSITY OF STURGEON FISH SPECIES (REVIEW)

Ribogospodarsʹka Nauka Ukraïni, 2016
Purpose. In recent years, cryopreservation of reproductive products has widely been used as one of the accessible and in some cases the only ways of preserving and supporting the number of endangered fish species including sturgeon fish species ...
I. Kononenko, V. Bekh
doaj   +1 more source

CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation

Advanced Science, EarlyView.
CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu, Zhou Jing Zhang, Jing Jin, Hai Yuan Xu, Ya Xin Gu, Qian Qian Yang, You Lang Zhou   +6 more
wiley   +1 more source

MODELING OF THE KINETICS OF CRYOGENIC FREEZING OF LIMA BEAN SEEDS AS A FUNCTION OF INITIAL WATER CONTENT [PDF]

Engenharia Agrícola
Cryopreservation is a technique used to preserve genetic material at ultra-low temperatures in cryogenic germplasm banks. In order to enable the cryopreservation of a seed, it is necessary to study its appropriate freezing temperature and its water ...
Karina M da F. Luciano, Mario E. R. M. Cavalcanti Mata, Mauri Fortes, Maria E. M. Duarte   +3 more
doaj   +2 more sources

Spontaneous Cyclic Levitation of Glycerol‐Water Droplets at Low Pressures

Advanced Science, EarlyView.
Under low pressure, a minute glycerol addition transforms the chaotic dynamics of freezing water droplets into cyclic levitation. Freeze‐concentration preserves liquid pathways that relax expansion‐induced stress, while freezing point depression weakens asymmetric vaporization recoil.
Chen Xu, Renjie Hua, Wei Ma, Fuqiang Chu, Dong Liang, Xueshi Li, Qirui Zhang, Yuan Dong, Xuehu Ma, Xiao Yan, Shuhuai Yao   +10 more
wiley   +1 more source

Current status of sperm cryopreservation for fertility preservation prior to cancer treatment at Jichi Medical University Hospital [PDF]

, 2021
Objective: The objective of this study was to clarify the current status of sperm cryopreservation for fertility preservation prior to cancer treatment at Jichi Medical University Hospital.
Tsunoda, Hiromichi, Suzuki, Tatsuya, Matsubara, Shigeki, Ando, Satoshi, Fujimura, Tetsuya   +4 more
core  

Cryopreservation of Pancreatic Islets Experimental Data Repository 2022

, 2021
These are the raw data used to generate each figure for our paper under review in Nature MedicineNational Institutes of Health (R01DK131209), National Science Foundation (EEC 1941543)Bischof, John, C; Finger, Erik, B. (2022).
Bischof, John, C, Finger, Erik, B
core   +1 more source