A mixture of innate cryoprotectants is key for freeze tolerance and cryopreservation of a drosophilid fly larva [PDF]
Lukáš Kučera +12 more
openalex +1 more source
ABSTRACT Valvular heart disease (VHD) represents a significant global health challenge, affecting over 2.5% of the population and disproportionately impacting older adults due to age‐related degenerative processes. Current treatment options—mechanical and bioprosthetic valves—both present substantial limitations that impact patient quality of life and ...
Nikolaos P. Tzavellas +8 more
wiley +1 more source
Cryopreservation of the Kidney: A Feasibility Study Based on Cooling Rates
This project models the cryopreservation of a kidney submerged in liquid nitrogen. Attempts to cryopreserve whole organs have been unsuccessful in the past due to the formation of ice crystals in the intracellular fluid, which cause damage to the cells.
Malvica, Erica +4 more
core
Role of Seminal Exosomes in Reproduction
ABSTRACT Exosomes are small lipid bilayer vesicles, ranging from 30 to 150 nm in diameter, that are secreted by various cells and facilitate intercellular communication. They originate from the endosomal system and release their contents into the extracellular environment.
Shayesteh Mehdinejadiani +9 more
wiley +1 more source
ABSTRACT Despite modern bladder management methods, lower and upper urinary tract complications still contribute significantly to morbidity and diminished quality of life in persons with spinal cord injuries (SCI). Neurogenic overactive bladders often develop after SCI and this can result in loss of compliance, with concomitant urinary tract ...
Noor Al‐Khayat +5 more
wiley +1 more source
Unraveling Lyophilization and Redispersion Effects on Miktoarm Polymer-Based Nanoformulations. [PDF]
Yousefi Adlsadabad S +7 more
europepmc +1 more source
Sperm viability and quantity of mud crab, Scylla tranquebarica in different cryoprotectants [PDF]
Cheng Ann Chen +4 more
openalex
Signal transduction and the function of second messengers and protein kinases in the control of glycogenolysis and cryoprotectant production in freeze tolerant vertebrates. [PDF]
Clark Holden
openalex +1 more source
Buttressing ligand‐binding pockets in de novo designed NTF2‐like domains
Abstract NTF2‐like proteins are compact α + β fold domains with cone‐shaped architectures and internal pockets, making them attractive scaffolds for the de novo design of small‐molecule binders and enzymes. However, creating ligand‐binding pockets often compromises folding stability, posing a key challenge in de novo protein design.
Marta Nadal +6 more
wiley +1 more source
A Cryopreservation and Regeneration Protocol for Embryogenic Callus of <i>Larix olgensis</i>. [PDF]
Wang C +8 more
europepmc +1 more source

