Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective [PDF]
Advanced ScienceCryopreservation is the storage of biological materials like cells, tissues, or even organs at cryogenic temperatures. This technology is a key enabler for biobanking, reproductive medicine, and cell therapy, and is positioned as a vital part of the ...
Dominika Wilczok +4 more
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Vitrification Ability of Combined and Single Cryoprotective Agents [PDF]
Plants, 2021 Cryoprotective agents (CPA) are an important part of many current vitrification methods. The vitrification ability of CPAs influences the probability of the glass transition and water crystallization occurrence.
Milos Faltus +2 more
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Impact of cryoprotective agents on human gut microbes and in vitro stabilized artificial gut microbiota communities [PDF]
Microbial BiotechnologyThe availability of microbial biobanks for the storage of individual gut microbiota members or their derived and artificially assembled consortia has become fundamental for in vitro investigation of the molecular mechanisms behind microbe–microbe and/or ...
Giulia Alessandri +7 more
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Tailoring Freeze-Drying for Starter Cultures Preservation: A Case Study with Lactiplantibacillus plantarum [PDF]
FoodsFreeze-drying is a crucial technique for preserving bacterial strains, yet its efficiency depends heavily on the precise selection of protective agents.
Antoni Miecznikowski +3 more
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Cryopreservation of ovarian tissue – what's known so far and future perspectives [PDF]
Frontiers in Reproductive HealthBackgroundCryopreservation is widely used across the life sciences to enable long-term storage of living cells and tissues for research or later clinical use. Its core principle is the arrest of biological activity at extremely low temperatures.
Sabine Eberhart +5 more
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Cryoprotective agents affect amino acids incorporation into total proteins in cells of lymphoid organs and liver of experimental animals [PDF]
The Ukrainian Biochemical Journal, 2020 The effect of penetrating (glycerol, DMSO) and poorly penetrating (PEG-400) cryoprotective agents on labeled amino acids incorporation into de novo synthesized proteins in the cells of mice thymus, lymph nodes, spleen and cell-free rat liver extract was ...
A. K. Gulevskyy +2 more
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Permeability and Toxicity of Cryoprotective Agents in Silkworm Embryos: Impact on Cryopreservation [PDF]
International Journal of Molecular SciencesHiroki Sakai +2 more
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Natural Cryoprotective and Cytoprotective Agents in Cryopreservation: A Focus on Melatonin
Molecules, 2022 Cryoprotective and cytoprotective agents (Cytoprotective Agents) are fundamental components of the cryopreservation process. This review presents the essentials of the cryopreservation process by examining its drawbacks and the role of cytoprotective ...
Giada Marcantonini +10 more
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Ultrasonics Sonochemistry, 2023 Lactic acid bacteria (LAB) are being used for probiotic and starter cultures to prevent global damage to microbial cells. To retain the benefits of LAB in the commercially used powdered form, highly efficient cryoprotective agents are required during the
Yeong Yeol Kim +5 more
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Modification of cellular membranes conveys cryoprotection to cells during rapid, non-equilibrium cryopreservation. [PDF]
PLoS ONE, 2018 Rapid cooling and re-warming has been shown promising to cryopreserve living cells, which cannot be preserved by conventional slow freezing methods. However, success is limited by the cytotoxicity of highly concentrated cryoprotective agents.
Jan Huebinger
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